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A prospective study about physical growth of children from birth to 2 years old born full-term

Lili Huang1, Sufei Yang1, Fan Yang1

  • 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Chengdu, Sichuan, China.

Journal of Paediatrics and Child Health
|August 2, 2018
PubMed

Insights

Most full-term infants born small-for-gestational-age (SGA) achieve catch-up growth by age two. Weight catch-up velocity generally surpassed length catch-up velocity in these children.

Area of Science:

  • Pediatrics
  • Human Growth and Development
  • Neonatology

Background:

  • Small-for-gestational-age (SGA) infants born full-term represent a distinct cohort with potential growth concerns.
  • Understanding their growth trajectory is crucial for early intervention and long-term health outcomes.

Purpose of the Study:

  • To evaluate the growth trends and catch-up growth patterns of full-term infants born small-for-gestational-age (SGA) from birth to two years.
  • To analyze growth velocity and deviations in weight, length, and head circumference.

Main Methods:

  • Prospective follow-up of 850 full-term SGA infants from birth to 24 months.
  • Regular monitoring of weight, length, and head circumference at 3, 6, 12, 18, and 24 months.
  • Standardized z-scores and delta z-scores were used to assess catch-up growth and growth velocity.

Main Results:

  • Over 95% of SGA infants achieved full catch-up growth within two years, with no significant gender differences.
  • Initial growth parameters (weight, length, head circumference) showed lower z-scores at 3-6 months, improving over time.
  • The prevalence of underweight and short stature significantly decreased by 6 months, with only 2.97% underweight and 2.67% short stature at 24 months.

Conclusions:

  • The majority of full-term SGA infants demonstrate significant catch-up growth within the first year of life.
  • Weight catch-up velocity consistently exceeded length catch-up velocity across all follow-up visits.
  • Further research is recommended to ascertain the long-term growth outcomes for this population.
Abstract

Keywords:
catch-upphysical growthsmall-for-gestational-age

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