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Updated: Feb 7, 2026

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
Published on: October 24, 2025
A method to repair the recurrent laryngeal nerve during thyroidectomy
Angela Gurrado1, Alessandro Pasculli1, Angela Pezzolla1
1From the Unit of Endocrine, Digestive, and Emergency Surgery, Department of Biomedical Sciences and Human Oncology (Gurrado, Pasculli, Di Meo, Testini), the Unit of Laparoscopic Surgery, Department of Emergency and Organ Transplantation, (Pezzolla), the Unit of Otorhinolaryngology, Department of Biomedical Sciences, Neurosciences and Sense Organs (Fiorella) and the Unit of Physical Medicine and Rehabilitation, Department of Neurological and Psychiatric Sciences (Cortese), University Medical School "A Moro" of Bari, Bari, Italy; and the Unit of Endocrine Surgery, Department of Surgical Sciences, Radiology and Dentistry, Santa Maria Hospital of Terni, University of Perugia, Perugia, Italy (Avenia).
Immediate microsurgical repair of the recurrent laryngeal nerve (RLN) after thyroidectomy can restore vocal cord function. This study shows significant voice quality improvements following RLN reconstruction in patients with iatrogenic nerve injury.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Thyroid Surgery
Background:
- Vocal cord palsy (VCP) is a common complication after thyroidectomy.
- Recurrent laryngeal nerve (RLN) injury can lead to significant voice impairment.
- Intraoperative management of iatrogenic RLN injury is crucial for functional outcomes.
Purpose of the Study:
- To evaluate the outcomes of immediate intraoperative reconstruction of the recurrent laryngeal nerve (RLN).
- To assess voice quality and aspiration in patients undergoing RLN repair following thyroidectomy.
Main Methods:
- Retrospective analysis of 917 thyroidectomy patients (2000-2015).
- Identified 12 patients with RLN injury, categorized into two groups based on intraoperative findings or postoperative VCP.
- Group A (n=5) underwent immediate microsurgical primary RLN repair; outcomes assessed via subjective (voice, aspiration) and objective (GRBAS scale, laryngoscopy) measures at 3 and 9 months.
Main Results:
- In Group A, significant improvements in roughness, breathiness, and strain were observed at 9 months compared to 3 months post-repair (p < 0.05).
- Immediate RLN reconstruction demonstrated positive trends in voice quality and reduced aspiration.
Conclusions:
- Immediate microsurgical reconstruction of the recurrent laryngeal nerve (RLN) appears to yield excellent postoperative phonatory function.
- Further multicenter studies are warranted to validate these findings.
- Prompt surgical intervention for RLN injury can mitigate long-term vocal dysfunction.
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