Generation of ChIP-Loop Libraries

Related Experiment Video

Updated: Feb 7, 2026

Generation of Native Chromatin Immunoprecipitation Sequencing Libraries for Nucleosome Density Analysis
10:05

Generation of Native Chromatin Immunoprecipitation Sequencing Libraries for Nucleosome Density Analysis

Published on: December 12, 2017

22.9K

Tae Hoon Kim, Job Dekker

    Cold Spring Harbor Protocols
    |August 3, 2018
    PubMed

    More Related Videos

    Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing08:19

    Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing

    Published on: July 7, 2020

    11.4K
    Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells08:34

    Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells

    Published on: December 10, 2014

    19.1K

    Related Concept Videos

    Feedback Loops01:01

    Feedback Loops

    In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
    64.5K
    Open and closed-loop control systems01:17

    Open and closed-loop control systems

    Control systems are foundational elements in automation and engineering. They are broadly categorized into open-loop and closed-loop systems. These classifications hinge on the presence or absence of feedback mechanisms, significantly influencing the system's performance, complexity, and application.
    An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
    1.7K
    Positive and Negative Feedback Loops01:18

    Positive and Negative Feedback Loops

    Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires  maintaining an internal dynamic equilibrium:
    25.3K
    Chromatin Immunoprecipitation- ChIP02:36

    Chromatin Immunoprecipitation- ChIP

    Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
    Types of ChIP
    ChIP can be divided into two types - X-ChIP and N-ChIP. X-ChIP involves in vivo cross-linking of histones and regulatory proteins to DNA, fragmenting the DNA by sonication, and isolating the protein-DNA...
    12.5K
    Cell Signaling Feedback Loops01:07

    Cell Signaling Feedback Loops

    Positive and negative feedback loops are crucial for regulating biological signaling systems. These feedback loops are processes that connect output signals to their inputs.
    Negative feedback loops
    Most signaling systems have negative feedback loops that can perform different functions such as output limiter, and adaptation.
    Output limiter
    Upon receiving an input signal, the cellular response rapidly increases until a threshold is reached. Beyond this threshold, a negative feedback loop...
    7.4K
    Magnetic Field Of A Current Loop01:16

    Magnetic Field Of A Current Loop

    Consider a circular loop with a radius a, that carries a current I. The magnetic field due to the current at an arbitrary point P along the axis of the loop can be calculated using the Biot-Savart law.
    6.4K