Recent progress of sample stacking in capillary electrophoresis (2016-2018).

Area of Science:

• Analytical Chemistry
• Separation Science

Background:

• Electrophoretic sample stacking is a key capillary electrophoresis (CE) technique.
• It concentrates trace analytes into a compact zone for enhanced detection.

Purpose of the Study:

• To provide a comprehensive review of electrophoretic sample stacking techniques.
• To survey over 120 research papers published between Q2 2016 and Q1 2018.
• To organize findings based on stacking principles.

Main Methods:

• Literature review and synthesis of published research.
• Categorization of stacking techniques including Kohlrausch stacking, pH-dependent stacking, and electrokinetic chromatography.
• Extraction of procedural details, electrolytes, detectors, and sensitivity data.

Main Results:

• The review covers diverse stacking principles and their applications.
• Detailed information on experimental procedures, reagents, and detection limits is compiled.
• Excludes transient isotachophoresis, which is covered elsewhere.

Conclusions:

• Electrophoretic sample stacking continues to evolve with various innovative techniques.
• This review serves as a valuable resource for researchers in CE and analytical chemistry.
• The compiled data aids in understanding and applying different stacking methods for trace analyte analysis.