Endoglin Targeting in Colorectal Tumor Microenvironment.

Lisa M Becker1, Valerie S LeBleu2

  • 1Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Summary

Endoglin, a TGFβ/BMP-9 coreceptor, is a potential antiangiogenic target for colorectal cancer. Neutralizing endoglin may also combat metastasis facilitated by cancer-associated fibroblasts.

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