Related Experiment Video
Updated: Feb 7, 2026

Chemical Dimerization-Induced Protein Condensates on Telomeres
Published on: April 12, 2021
Vielopsides A-E, five new guaiane-type sesquiterpenoid dimers from Xylopia vielana
Yang-Guo Xie1, Guo-Jing Wu1, Tao-Fang Cheng1
1Shanghai Key Laboratory of Antimicrobias, New Drug Discovery, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, PR China.
Abstract:
Five new guaiane-type sesquiterpenoid dimers vielopsides A-E, connecting patterns through two direct CC bonds (C-2 to C-2', C-4 to C-1'), were isolated from the roots of Xylopia vielana. Their absolute configurations were established by NOE analysis, the Cu Kα X-ray crystallographic and circular dichroism (CD) experiment. Among them, compound 5 showed moderate activity IC50 values of 33.8 μM on NO production in RAW 264.7 macrophages.
Related Concept Videos
Types of RNA
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of Hormones
Types of Selection
Types of Skewness
For instance, in the middle of a pandemic, the geographical distribution of vaccine coverage may be positively skewed towards populations in the global north countries. However,...
Types of Damping
Types of Functions I

