Related Experiment Video
Updated: Feb 7, 2026

Isolation and Biophysical Study of Fruit Cuticles
Published on: March 30, 2012
[Study on Alkaloids of Fruit from Macleaya cordata]
Objective:
To study the alkaloids from the fruit of Macleaya cordata.
Methods:
The alkaloids were isolated and purified by silica gel column chromatography and preparative high performance liquid chromatography,and the structures were elucidated based on the spectral data.
Results:
Eight alkaloids were obtained from the fraction of ethanol extract and identified as 6-cyanodihydrosanguinarine( 1),6-acetonyldihydrosanguinarine( 2),6-acetonyldihydrochelerythrine( 3),chelerythrine( 4),dihydrochelerythrine( 5),13,14-dehydrogen-N-methyl-coptisine( 6),N-methyl-canadine( 7) and berberine( 8).
Conclusion:
Compounds 1 and 6 are new nature products,and compound 7 is isolated from this plant for the first time.
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