Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Phosphorus Cycle01:21

The Phosphorus Cycle

44.0K
Unlike carbon, water, and nitrogen, phosphorus is not present in the atmosphere as a gas. Instead, most phosphorus in the ecosystem exists as compounds, such as phosphate ions (PO43-), found in soil, water, sediment and rocks. Phosphorus is often a limiting nutrient (i.e., in short supply). Consequently, phosphorus is added to most agricultural fertilizers, which can cause environmental problems related to runoff in aquatic ecosystems.
44.0K
Detection of Black Holes01:10

Detection of Black Holes

2.6K
Although black holes were theoretically postulated in the 1920s, they remained outside the domain of observational astronomy until the 1970s.
Their closest cousins are neutron stars, which are composed almost entirely of neutrons packed against each other, making them extremely dense. A neutron star has the same mass as the Sun but its diameter is only a few kilometers. Therefore, the escape velocity from their surface is close to the speed of light.
Not until the 1960s, when the first neutron...
2.6K
Passive Filters01:27

Passive Filters

1.0K
Passive filters are utilized to shape the frequency spectrum of signals across a diverse array of applications. These filters, using only passive elements like resistors (R), inductors (L), and capacitors (C), are capable of selectively allowing or blocking certain frequency ranges without the need for external power sources.
Low-Pass Filters
Low-pass filters are designed to transmit signals with frequencies lower than the cutoff frequency, ωc, and attenuate those above it. The cutoff...
1.0K
Active versus Passive Immunity01:31

Active versus Passive Immunity

10.9K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
10.9K
Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

7.0K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
7.0K
Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

1.4K
Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal multiomics profiling of extracorporeal cross-circulation with pig liver xenografts in human decedents.

Nature medicine·2026
Same author

Gut microbiota in a Saudi population with chronic kidney disease.

World journal of nephrology·2026
Same author

A Self-Powered Dressing Based on a Zn-Mo Galvanic Cell for Accelerated Wound Repair.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Differences in carbon sequestration capacity, rhizosphere microorganisms and metabolic functions among different herbaceous plants.

Frontiers in plant science·2026
Same author

Scenario-Driven Rapid Testing for Top Pathogens in Pediatric Respiratory Infections: Clinical and Economic Value from Emergency Triage to Precision Anti-Infective Management in the PICU.

Pathogens (Basel, Switzerland)·2026
Same author

Leukemia inhibitory factor drives malignant progression in lung squamous cell carcinoma via the PI3K/AKT/GSK-3β/β-catenin axis.

Journal of molecular histology·2026

Related Experiment Video

Updated: Feb 6, 2026

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

9.9K

Black Phosphorus Nanosheets Passivation Using a Tripeptide.

Huaying Wang1, Kuan Hu1,2,3, Zhe Li1,2,3

  • 1CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.

Small (Weinheim an Der Bergstrasse, Germany)
|August 8, 2018
PubMed
Summary

Researchers developed a new method to stabilize 2D black phosphorus (BP) using a tripeptide Fmoc-Lys-Lys-Phe (Fmoc-KKF). The resulting BP@FKK complex shows enhanced stability and cell compatibility, overcoming limitations of bare BP for practical applications.

Keywords:
biocompatibilityblack phosphoruspeptidephotothermalstability

More Related Videos

Laboratory-determined Phosphorus Flux from Lake Sediments as a Measure of Internal Phosphorus Loading
10:49

Laboratory-determined Phosphorus Flux from Lake Sediments as a Measure of Internal Phosphorus Loading

Published on: March 6, 2014

17.8K
Preparation of Carbon Nanosheets at Room Temperature
10:44

Preparation of Carbon Nanosheets at Room Temperature

Published on: March 8, 2016

12.6K

Related Experiment Videos

Last Updated: Feb 6, 2026

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

9.9K
Laboratory-determined Phosphorus Flux from Lake Sediments as a Measure of Internal Phosphorus Loading
10:49

Laboratory-determined Phosphorus Flux from Lake Sediments as a Measure of Internal Phosphorus Loading

Published on: March 6, 2014

17.8K
Preparation of Carbon Nanosheets at Room Temperature
10:44

Preparation of Carbon Nanosheets at Room Temperature

Published on: March 8, 2016

12.6K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • 2D black phosphorus (BP) possesses unique electronic, photonic, and mechanical properties, attracting significant research interest.
  • The practical application of BP is hindered by its inherent instability and rapid degradation.
  • Existing passivation strategies, such as metal coordination or polymer modification, raise concerns regarding potential long-term health effects.

Purpose of the Study:

  • To develop a novel, biocompatible surface modification strategy for 2D black phosphorus (BP).
  • To enhance the stability and lifespan of BP nanosheets.
  • To evaluate the cell compatibility and cellular uptake of the modified BP.

Main Methods:

  • Synthesis of a tailored tripeptide, Fmoc-Lys-Lys-Phe (Fmoc-KKF).
  • Surface modification of BP nanosheets using the synthesized Fmoc-KKF to create the BP@FKK complex.
  • Comparative analysis of the stability, degradation rates, cell compatibility, and cellular uptake of bare BP versus BP@FKK.

Main Results:

  • The BP@FKK complex demonstrated significantly improved stability and an extended lifespan compared to bare BP.
  • Bare BP exhibited rapid degradation, while the BP@FKK complex showed excellent preservation.
  • BP@FKK exhibited favorable cell compatibility and enhanced cellular uptake compared to bare BP.

Conclusions:

  • The Fmoc-KKF tripeptide serves as an effective and biocompatible agent for stabilizing 2D black phosphorus.
  • The developed BP@FKK complex overcomes the instability limitations of bare BP, paving the way for broader applications.
  • This strategy offers a promising alternative to conventional passivation methods, addressing potential health concerns associated with metal or polymer modifications.