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Updated: Feb 6, 2026

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
Published on: August 24, 2019
Surgical Resection Of Thoracic Aortic Aneurysms In Wiskott-Aldrich Syndrome
Mehmet Akif Onalan1, Omer Ali Sayin2, Emin Tireli2
1Department of Cardiovascular Surgery, Sanlıurfa Mehmet Akif Inan Training and Research Hospital, Sanliurfa, Turkey.
Abstract:
Aortic aneurysms are a rare condition in children. Wiskott-Aldrich syndrome is a primary immunodeficiency characterized by infections, thrombocytopenia, and eczema. Aortitis and aneurysm formation seem to be progressive in patients with Wiskott-Aldrich syndrome. The risk of death from aneurysmal rupture in patients with Wiskott-Aldrich syndrome is high and surgery is required for resection of aneurysms. We report a case where a successful resection of a descending thoracic aneurysm. We present a-12 year-old child with this syndrome who underwent a one-stage descending aortic aneurysm repair under continuous visceral perfusion.Histologic examination showed the presence of an aortitis withgranulomatous inflammatory response and multinucleated cells.
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