Related Experiment Video
Updated: Feb 6, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
Published on: November 10, 2017
Direct cation exchange of surface ligand capped upconversion nanocrystals to produce strong luminescence
Ming Guan1, Zhiguang Zhou, Lefu Mei
1Institute for Biomedical Materials and Devices, School of Mathematical and Physical Sciences, Faculty of Science, University of Technology, Sydney, NSW 2007, Australia. Jiajia.Zhou@uts.edu.au.
Abstract:
We develop a facile and rapid cation exchange method for upconversion nanocrystals (UCNCs) without removing surface ligands. It avoids the tedious pretreatment of as-synthesized UCNCs, and the luminescent intensities of nanocrystals after Tb3+ exchange using the new method are much stronger than those of the nanocrystals obtained using conventional cation exchange in water.
Related Concept Videos
Titration Calculations: Strong Acid - Strong Base
A titration is carried out for 25.00 mL of 0.100 M HCl (strong acid) with 0.100 M of a strong base NaOH. The pH at different volumes of added base solution can be calculated as follows:
(a) Titrant volume = 0 mL. The solution pH is due to the acid ionization of HCl. Because this is a strong acid, the ionization is complete and the hydronium ion molarity is 0.100 M. The pH of the solution is then:
Strong Acid and Base Solutions
Crossed Aldol Reaction Using Strong Bases: Directed Aldol Reaction
Ligand Binding and Linkage
Ligand Binding Sites
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
Titration of a Strong Acid with a Strong Base

