Related Experiment Video
Updated: Feb 6, 2026
14:45
Laser Doppler Perfusion Imaging in the Mouse Hindlimb
Published on: April 18, 2021
6.7K
NORMATIVE VALUES FOR A NEW WATER-PERFUSED HIGH RESOLUTION MANOMETRY SYSTEM
Rogério Mariotto Bitetti da Silva1, Fernando A M Herbella1, Daniel Gualberto1
1Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Cirurgia, São Paulo, SP, Brasil.
Arquivos De Gastroenterologia
|August 9, 2018
Summary
This study establishes normative data for a new water-perfused high-resolution manometry (HRM) system. The findings indicate this low-cost HRM is suitable for clinical evaluation of esophageal motility.
Area of Science:
- Gastroenterology
- Physiology
- Medical Devices
Background:
- Esophageal manometry is crucial for assessing esophageal motility.
- High-resolution manometry (HRM) offers detailed topographic analysis.
- Both solid-state and water-perfused HRM systems are available.
Purpose of the Study:
- To determine normative data for a novel water-perfused HRM system.
- To validate the performance of a new HRM device for clinical application.
Main Methods:
- HRM was performed on 32 healthy volunteers under fasting conditions.
- A 24-channel, water-perfused catheter system was utilized for data acquisition.
- Key parameters including UES pressures, DCI, DL, break, and LES pressures were analyzed.
Main Results:
- Normative data (5-95th percentiles) were established for UES basal pressure, DL, DCI, break, LES basal pressure, and IRP.
- The HRM procedure was well-tolerated by all participants.
- Specific ranges for UES basal pressure (16.7-184.37 mmHg) and IRP (0.55-15.45 mmHg) were determined.
Conclusions:
- The developed water-perfused HRM system demonstrates adequate performance.
- The obtained normative values support the clinical utility of this low-cost HRM device.
- This study provides essential reference data for esophageal motility assessment.
Related Concept Videos
01:24Biodiversity and Human Values
17.1K
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
17.1K
01:29Professional Values
10.7K
Nurses are responsible for caring for patients during birth, death, illness, and healing. Professional values guide the decisions and actions that nurses make in their careers. If nurses know the decisions and actions to take, providing patients with exceptional care is possible.
The values that are the foundation of the nursing profession are altruism, autonomy, human dignity, and social justice.
First, altruism refers to the concern for the welfare and well-being of others without personal...
The values that are the foundation of the nursing profession are altruism, autonomy, human dignity, and social justice.
First, altruism refers to the concern for the welfare and well-being of others without personal...
10.7K
01:31Critical Values
10.4K
A critical value is a definite value obtained from a particular probability distribution at a predecided confidence level (or a predecided significance level) for a given population parameter. The critical value provides demarcation that separates the sample statistics that are likely to occur from the ones that are unlikely to occur based on the given probability distribution and the population parameter to be estimated. The critical value for normal distribution is obtained from the z...
10.4K
01:07z Scores and Unusual Values
11.0K
The z score is one of the three measures of relative standing. It describes the location of a value in a dataset relative to the mean. z scores are obtained after the standardization of the values in a dataset. The z score for the mean is 0.
This score indicates how far a value is from the mean in terms of standard deviation. For example, if a data value has a z score of +1, the researcher can infer that the particular data value is one standard deviation above the mean. If another data...
This score indicates how far a value is from the mean in terms of standard deviation. For example, if a data value has a z score of +1, the researcher can infer that the particular data value is one standard deviation above the mean. If another data...
11.0K
01:22Absolute and Local Extreme Values
84
The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
84
01:23States of Water
57.1K
Water exists in any one of the three classical states: solid (ice), liquid (water), and gas (steam or water vapor). The state of water depends on i) the intermolecular forces that draw molecules together and ii) the kinetic energy that leads to movements that pull them apart.
Water freezes when the intermolecular forces are greater than the kinetic energy. Unlike most other substances, water is less dense in its solid state than in its liquid state. This is because each water molecule can form...
Water freezes when the intermolecular forces are greater than the kinetic energy. Unlike most other substances, water is less dense in its solid state than in its liquid state. This is because each water molecule can form...
57.1K