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Prenatal Diet and Child Growth at 18 Months

Jodie M Dodd1,2, Jennie Louise3,4, Andrea R Deussen3

  • 1Discipline of Obstetrics and Gynaecology, Robinson Research Institute and jodie.dodd@adelaide.edu.au.

Pediatrics
|August 10, 2018
PubMed

Insights

An antenatal lifestyle intervention for overweight or obese pregnant women did not significantly impact child growth or adiposity by 18 months. This study found no evidence of altered child BMI or development from the intervention.

Area of Science:

  • Maternal and Child Health
  • Preventive Medicine
  • Pediatric Nutrition

Background:

  • Overweight and obesity in pregnancy are associated with adverse child outcomes.
  • Antenatal interventions aim to mitigate these risks.
  • Limited evidence exists on the long-term effects of such interventions on child development.

Purpose of the Study:

  • To evaluate the impact of an antenatal dietary and lifestyle intervention on children born to overweight or obese mothers.
  • To assess child outcomes at 18 months, including BMI, growth, neurodevelopment, and general health.

Main Methods:

  • Follow-up study of children from the Limiting Weight Gain in Overweight and Obese Women during Pregnancy to Improve Health Outcomes randomized trial.
  • Assessed 1602 children at 18 months using intention-to-treat analysis.
  • Primary outcome: child BMI z-scores >85th percentile; secondary outcomes: anthropometry, neurodevelopment, health, feeding.

Main Results:

  • No significant difference in the prevalence of child BMI z-scores >85th percentile between the lifestyle advice and standard care groups (47.11% vs 45.36%).
  • The intervention showed no statistically significant effects on child growth, adiposity, neurodevelopment, or feeding patterns.
  • Adjusted relative risk for high BMI was 1.04 (95% CI: 0.94 to 1.16).

Conclusions:

  • Antenatal dietary and lifestyle interventions for overweight/obese pregnant women do not appear to alter 18-month child growth and adiposity.
  • Further research may be needed to explore alternative or modified interventions.
  • Current evidence does not support this specific intervention for improving early childhood growth parameters.
Abstract

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