Related Experiment Video
Updated: Feb 6, 2026
08:25
Evaluating the Function of the Foot Core System in the Elderly
Published on: March 11, 2022
3.3K
Neuropsychological deficits in elderly with depression
Rupesh Ranjan1, Richa Priyamvada2, Gyanendra Kumar Jha3
1Department of Psychiatry, BMHRC, Bhopal, Madhya Pradesh, India.
Industrial Psychiatry Journal
|August 10, 2018
Summary
Elderly patients with depression exhibit significant neurocognitive deficits in areas like memory and speech compared to healthy older adults. Early identification and treatment are crucial for managing late-onset depression.
Area of Science:
- Neuropsychology
- Geriatric Psychiatry
- Cognitive Science
Background:
- Depression in elderly patients is linked to impaired cognitive functions, including attention and memory.
- Unhappy thoughts in depression can significantly reduce cognitive performance.
Purpose of the Study:
- To evaluate neuropsychological deficits in elderly individuals diagnosed with depression.
- To compare the cognitive performance of elderly depressive patients with age-matched healthy controls.
Main Methods:
- A sample of 30 elderly depressive patients and 30 normal controls (aged 60+) were selected.
- Diagnosis of depression was based on the International Classification of Diseases, Tenth Edition criteria.
- Participants completed the Geriatric Depression Scale and the Luria-Nebraska Neuropsychological Battery-1 (LNNB form-1).
Main Results:
- Depressive patients showed mild (21) to severe (9) levels of depression.
- No depression was observed in the control group.
- Elderly depressive patients exhibited significant impairments in receptive speech, arithmetic, memory, reading, writing, and expressive speech compared to controls.
Conclusions:
- Older adults with depression demonstrate more pronounced neurocognitive deficits than their non-depressed counterparts.
- Identifying and addressing these cognitive deficits is essential for comprehensive treatment of late-onset depression.
Related Concept Videos
01:05Long-term Depression
33.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K
01:03Long-term Depression
3.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
3.4K
03:12Freezing Point Depression and Boiling Point Elevation
40.3K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.3K
01:28Depressants
450
Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
450
01:18Depression: Overview
891
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
891
01:30Attention-Deficit/Hyperactivity Disorder
998
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
998