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Updated: Feb 6, 2026

Reusable Single Cell for Iterative Epigenomic Analyses
Published on: February 11, 2022
Highly sulphated cellulose: a versatile, reusable and selective desilylating agent for deprotection of alcoholic
Soma Shekar Dachavaram1, Narsimha R Penthala, Julie L Calahan
1Department of Pharmaceutical Sciences College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. PACrooks@uams.edu.
Abstract:
A mild, efficient and rapid protocol was developed for the deprotection of alcoholic TBDMS ethers using a recyclable, eco-friendly highly sulphated cellulose sulphate acid catalyst in methanol. This acid catalyst selectively cleaves alcoholic TBDMS ethers in bis-TBDMS ethers containing both alcoholic and phenolic TBDMS ether moieties.
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