Age-related network topological difference based on the sleep ECG signal
Guohun Zhu1, Cong Wang2, Feng Liu1
1School of ITEE, The University of Queensland, St Lucia, 4072, Brisbane, Australia.
Physiological Measurement
|August 10, 2018
Summary
Age-related differences in sleep electrocardiogram (ECG) network properties were identified. These network variations show potential for sleep stage classification and disorder diagnosis.
Area of Science:
- Cardiovascular Physiology
- Network Science
- Sleep Medicine
Background:
- Age significantly impacts brain network characteristics during sleep (EEG/fMRI).
- Limited understanding exists on age-related ECG network properties across sleep stages.
Purpose of the Study:
- To explore age-related scale-free and small-world network properties of ECG signals.
- To investigate how these network properties change during different sleep stages (Wakeful, Light Sleep, Deep Sleep, REM).
Main Methods:
- Analysis of ECG signals from male subjects divided into younger (<=40) and older (>40) age groups.
- Evaluation of scale-free network parameters (mean degree, clustering coefficient, path length).
- Assessment of small-world network properties across distinct sleep stages.
Main Results:
- Distinct scale-free network topologies were observed between age groups.
- Small-world properties were present in all sleep stages for both groups.
- The small-world index significantly decreased with age during Light Sleep and REM stages.
Conclusions:
- ECG network topology variations exhibit age-relevant differences.
- These age-related network changes in sleep ECG signals can potentially aid in sleep stage classification.
- Findings suggest utility for sleep disorder diagnosis based on ECG network analysis.
Related Concept Videos
01:13Insufficient Sleep and Sleep Deprivation
942
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
942
02:26Protein Networks
4.6K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.6K
01:24ECG Interpretation of Rhythms
14.1K
An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
14.1K
01:22Stages of Sleep
1.5K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.5K
02:18Network Covalent Solids
16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
01:11Understanding Sleep
1.6K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.6K