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Related Experiment Video

Updated: Feb 6, 2026

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Atrioventricular conduction defect associated with severe hyponatremia.

Turgut Karabag1, Belma Kalayci1, Muhammet Rasit Sayin1

  • 1Department of Cardiology, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey.

Clujul Medical (1957)
|August 11, 2018
PubMed
Summary

Hyponatremia, a common electrolyte disorder, can cause neurological symptoms. This case study shows that hyponatremia can lead to complete atrioventricular block in elderly patients, which is reversible with sodium replacement therapy.

Keywords:
atrioventricular blockhyponatremiathiazide diuretics

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Area of Science:

  • Internal Medicine
  • Cardiology
  • Nephrology

Background:

  • Hyponatremia is the most common electrolyte disorder in hospitalized patients.
  • It is frequently observed in elderly individuals, especially those with cardiac conditions.
  • Symptoms range from neurological to gastrointestinal disturbances.

Observation:

  • A case of complete atrioventricular block in an elderly patient post-aortic valve replacement is presented.
  • The patient was concurrently using thiazide medication.
  • No other underlying cause for the electrolyte imbalance was identified.

Findings:

  • Complete atrioventricular block significantly improved following sodium replacement therapy.
  • This suggests a direct link between hyponatremia and the observed cardiac arrhythmia.
  • Thiazide use may have contributed to the development of hyponatremia.

Implications:

  • Highlights the importance of considering hyponatremia in elderly patients presenting with cardiac conduction abnormalities.
  • Emphasizes the potential reversibility of certain cardiac issues with electrolyte correction.
  • Suggests careful monitoring of electrolytes in patients on thiazide diuretics, particularly those with cardiac conditions.