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Polymer coatings based on sulfonated-poly-ether-ether-ketone films for implant dentistry applications
R S Brum1, P R Monich2, M C Fredel2
1Center for Research on Dental Implants (CEPID), School of Dentistry (ODT), Federal University of Santa Catarina (UFSC), Florianopolis/SC, 88040-900, Brazil. renatasbrum@live.com.
Journal of Materials Science. Materials in Medicine
|August 11, 2018
Summary
This study developed sulfonated poly-ether-ether-ketone (SPEEK) coatings on PEEK substrates for biomedical uses. While SPEEK coatings modified PEEK surfaces, they did not demonstrate significant bioactivity in simulated body fluid, requiring further development.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Surface Engineering
Background:
- Poly-ether-ether-ketone (PEEK) is a widely used biocompatible polymer in biomedical applications.
- Sulfonation of PEEK (SPEEK) has been explored to enhance its properties for enhanced biomedical utility.
- Developing functionalized PEEK surfaces is crucial for improving implant performance and osseointegration.
Purpose of the Study:
- To synthesize and characterize sulfonated PEEK (SPEEK) coatings on PEEK substrates.
- To evaluate the physicochemical properties and surface characteristics of the modified PEEK materials.
- To assess the bioactivity of SPEEK-coated PEEK in simulated body fluid (SBF).
Main Methods:
- Biomedical grade PEEK was functionalized with sulfuric acid to produce SPEEK.
- SPEEK was dissolved in Dimethyl sulfoxide (DMSO) or Dimethylformamide (DMF) and coated onto PEEK substrates (bars and cylinders).
- Characterization involved FTIR, XRD, SEM, contact angle measurements, and bioactivity assessment in SBF with subsequent analysis (SEM, EDX, FTIR).
Main Results:
- FTIR and XRD confirmed the successful sulfonation and semicrystallinity of PEEK and SPEEK.
- SPEEK/DMF coatings showed significant physicochemical modifications, while SPEEK/DMSO coatings resulted in more regular, hydrophobic surfaces.
- Calcium precipitates formed on both SPEEK/DMSO and SPEEK/DMF coated samples in SBF, but bioactivity was not confirmed.
Conclusions:
- SPEEK coatings on PEEK substrates exhibit interesting surface properties, with DMF and DMSO influencing surface characteristics differently.
- The formation of calcium precipitates suggests some interaction with biological fluid, but the materials were not deemed bioactive.
- Further improvements in SPEEK film production and comprehensive biological testing are necessary to optimize these coatings for biomedical applications.
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