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Functionalization of a Volume-Stable Collagen Matrix Using Liquid Platelet-Rich Fibrin: A Case Report Presenting a

Roberta Michels1, Gabriel Leonardo Magrin1, Acc Cruz1

  • 1Center for Education and Research on Dental Implants (CEPID), Post-Graduate Program in Dentistry (PPGO), Federal University of Santa Catarina (UFSC), Florianópolis, Brazil.

Case Reports in Dentistry
|April 3, 2023
PubMed
Summary
This summary is machine-generated.

A novel technique using a collagen matrix with injectable platelet-rich fibrin (i-PRF) effectively covered multiple gingival recessions. This method reduced patient morbidity by avoiding connective tissue grafting.

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Area of Science:

  • Periodontology
  • Regenerative Dentistry
  • Biomaterials Science

Background:

  • Gingival recession affects numerous patients, leading to aesthetic concerns and potential tooth sensitivity.
  • Autogenous connective tissue grafts are the gold standard but involve donor site morbidity.
  • Minimally invasive techniques are sought to improve patient outcomes and reduce surgical trauma.

Observation:

  • A patient with multiple anterior maxillary gingival recessions was treated using a coronally advanced flap.
  • A volume-stable collagen matrix was saturated with injectable platelet-rich fibrin (i-PRF) and used as a substitute for autogenous connective tissue.
  • i-PRF was prepared from the patient's blood via centrifugation at 400g for 3 minutes.

Findings:

  • The combined therapy achieved a mean root coverage of 83% after 12 months.
  • Long-term follow-up at 30 months showed stable results with only minor changes.
  • This approach successfully treated multiple gingival recessions, demonstrating significant clinical efficacy.

Implications:

  • This i-PRF-functionalized collagen matrix offers a viable, less invasive alternative to traditional grafting for root coverage.
  • The technique shows potential for widespread adoption in treating complex gingival recession cases.
  • Reduced morbidity and successful root coverage highlight the therapeutic potential of combining biomaterials with platelet concentrates.