Volume-Stable Collagen Matrix With or Without Platelet-Rich Fibrin Impregnation for Multiple Gingival Recessions: A...

Area of Science:

• Periodontology
• Regenerative Dentistry
• Biomaterials in Oral Surgery

Background:

• Gingival recession affects numerous patients, impacting oral health and aesthetics.
• The coronally advanced flap technique is a common surgical approach for root coverage.
• Volume-stable collagen matrices are utilized to enhance surgical outcomes.

Purpose of the Study:

• To evaluate if incorporating platelet-rich fibrin (PRF) into a collagen matrix improves gingival recession reduction.
• To compare clinical, esthetic, and patient-reported outcomes between PRF-augmented and non-augmented matrices.
• To assess the efficacy of PRF in conjunction with a collagen matrix for treating gingival recessions.

Main Methods:

• A split-mouth randomized clinical trial was conducted on patients with maxillary RT1 recessions.
• Participants received either a PRF-impregnated or a non-impregnated collagen matrix with a coronally advanced flap.
• Clinical parameters, esthetic scores, and patient-reported outcomes were measured at baseline and 6 months.

Main Results:

• Both treatment groups showed significant improvement in recession depth over 6 months.
• No statistically significant intergroup differences were observed for recession depth, keratinized tissue width, probing depth, or clinical attachment level.
• Evaluations of Root Coverage Esthetic Score (RES) and patient-reported outcome measures (PROMs) revealed no significant differences between the PRF-augmented and control groups.

Conclusions:

• The addition of PRF to a volume-stable collagen matrix did not yield superior results for gingival recession depth reduction.
• PRF augmentation did not significantly enhance clinical, esthetic, or patient-reported outcomes compared to the non-augmented matrix.
• Further research may be needed to explore the role of PRF in periodontal regeneration.