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The isolation of Streptococcus pneumoniae from bile
The Journal of Infection
|March 1, 1986
Summary
Streptococcus pneumoniae, a common cause of pneumonia, was found colonizing the bile ducts in two adults with obstructive jaundice. This indicates a potential link between pneumococcal infections and biliary tract disease.
Area of Science:
- Microbiology
- Infectious Diseases
- Hepatology
Background:
- Extrahepatic obstructive jaundice can predispose patients to biliary tract infections.
- The role of Streptococcus pneumoniae in biliary tract infections is not well-established.
Observation:
- Streptococcus pneumoniae was isolated from the bile of two adults with obstructive jaundice.
- The organism was consistently recovered over 10 days, suggesting established biliary colonization.
- Pneumococci were found at multiple sites in the biliary tract during surgery.
Findings:
- Both isolated pneumococcal strains showed typical morphology and biochemical characteristics.
- The strains were susceptible to optochin, a key diagnostic marker.
- The bacteria demonstrated characteristic solubility in human and ox bile, and bile salts.
Implications:
- This study highlights Streptococcus pneumoniae as a potential pathogen in biliary tract infections.
- Understanding pneumococcal behavior in the biliary system may inform treatment strategies for obstructive jaundice.
- Further research is warranted to explore the pathogenesis and clinical significance of pneumococcal biliary colonization.