Penile Median Raphe Anomalies as an Indicator of Megameatus Intact Prepuce Anomaly in Children Undergoing Routine Circumcision
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Published on: June 3, 2022
Mohamed A Baky Fahmy1, Alaa A El Shenawy2, Aymen Altramsy3
1AL-Azhar University, Faculty of Medicine, Pediatric Surgery Department, Cairo, Egypt.
Objective:
To arouse the suspicious for early diagnosis and hence, proper management of megameatus with an intact prepuce (MIP), as there is no external clue for detection of such cases, which usually come to light for the first time in a boy who is about to retract his prepuce or during neonatal circumcision.
Materials And Methods:
Examination of neonates and infants coming to circumcision clinic to detect congenital genitourinary anomalies. Evaluation of 12,518 neonates and infants coming for ritual circumcision from 2006-2017, who were examined thoroughly to detect any incidental congenital genitourinary anomalies. Fifteen of them were diagnosed to have a MIP anomaly. They were investigated to perceive any associated median raphe (MR) anomalies. Sensitivity, positive predictive value, specificity, and negative predictive value of MR anomalies in cases of MIP were estimated and compared with other children who had a normally positioned meatus.
Results:
Overall incidence of MIP in this group of babies was 0.12%. Twelve of 15 cases (80%) with MIP had 19 forms of MR anomalies; mainly raphe deviation in 6 cases, hyperpigmented raphe in 6, prominent raphe in 4, and bifurcation in 3 cases. Three cases had a redundant long prepuce, and 1 had paraphimosis after preputial retraction, otherwise no other genitourinary anomalies could be detected in those cases.
Conclusion:
MR anomalies, mainly deviation and hyperpigmented prominent raphe, are significant indictors for the presence of an invisible MIP anomaly. Abnormally redundant long prepuce may be seen in such cases, but this is not common.
Insights
Median raphe anomalies, such as deviation and hyperpigmentation, are key indicators for detecting megameatus with an intact prepuce (MIP) in infants. Early diagnosis of MIP is crucial for timely management.
Area of Science:
- Pediatric Urology
- Congenital Genitourinary Anomalies
Background:
- Megameatus with an intact prepuce (MIP) is a congenital condition often undetected until later childhood.
- Diagnosis typically occurs incidentally during attempts at preputial retraction or neonatal circumcision.
Purpose of the Study:
- To identify indicators for the early diagnosis of megameatus with an intact prepuce (MIP).
- To investigate the association between median raphe (MR) anomalies and MIP.
- To establish the diagnostic value of MR anomalies for MIP detection.
Main Methods:
- Prospective examination of 12,518 neonates and infants undergoing ritual circumcision.
- Detailed genitourinary anomaly screening, focusing on MIP and associated median raphe (MR) anomalies.
- Statistical analysis of MR anomalies' sensitivity, specificity, and predictive values in MIP cases.
Main Results:
- The incidence of MIP was found to be 0.12% in the studied cohort.
- Eighty percent (12/15) of MIP cases exhibited associated MR anomalies, including raphe deviation, hyperpigmentation, prominence, and bifurcation.
- Associated findings included redundant prepuce (3 cases) and paraphimosis (1 case); no other significant genitourinary anomalies were noted.
Conclusions:
- Median raphe anomalies, particularly deviation and hyperpigmented prominent raphe, serve as significant indicators for the presence of undiagnosed MIP.
- While redundant prepuce can occur, it is not a consistent finding in MIP.
- Routine examination for MR anomalies during neonatal circumcision can aid in the early detection of MIP.
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