Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Comparing Copy Number Variations and SNPs02:26

Comparing Copy Number Variations and SNPs

18.8K
Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
18.8K
Comparative Excretory Systems02:24

Comparative Excretory Systems

26.7K
Animals have evolved different strategies for excretion, the removal of waste from the body. Most waste must be dissolved in water to be excreted, so an animal’s excretory strategy directly affects its water balance.
26.7K
Comparing Experimental Results: Student's t-Test01:09

Comparing Experimental Results: Student's t-Test

6.0K
The t-test is a statistical method used to compare the sample mean with a population mean or compare two means from two data sets. The test statistic is calculated from the standard deviation, mean, and number of measurements in the data set at a selected confidence interval and then compared to a table of critical values at this confidence level. If the test statistic is smaller than the critical value, the null hypothesis is accepted. In this case, we state that the difference between the...
6.0K
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

605
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
605
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

16.4K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
16.4K
Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility02:34

Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility

51.6K
Intermolecular forces are attractive forces that exist between molecules. They dictate several bulk properties, such as melting points, boiling points, and solubilities (miscibilities) of substances. Molar mass, molecular shape, and polarity affect the strength of different intermolecular forces, which influence the magnitude of physical properties across a family of molecules.
Temporary attractive forces like dispersion are present in all molecules, whether they are polar or nonpolar. They...
51.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neural Correlates of Maternal Posttraumatic Stress in the First Postpartum Year: Blunted Salience and Prefrontal Responses to Infant Distress.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2026
Same author

The genetic landscape of human functional brain connectivity.

Nature communications·2026
Same author

Rare-variant aggregation highlights disease-linked genes associated with brain volume variation.

American journal of human genetics·2026
Same author

Investigating the methodological foundation of lesion network mapping.

Nature neuroscience·2026
Same author

Network-based analysis of differential white matter connectivity in major depressive disorder with and without comorbid anxiety.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

The transition to human fatherhood involves increased brain activation to infant stimuli in regions involved with reward and motivation.

Journal of neuroendocrinology·2025
Same journal

"Mind Over Muscle": Neural and Biomechanical Signatures of Expertise in Early Stone Tool Use.

Brain, behavior and evolution·2026
Same journal

A step forward in encephalization: the virtual endocast of the Middle Pleistocene hominin from Ceprano, Italy.

Brain, behavior and evolution·2026
Same journal

Anatomical and Volumetric Description of the Baird's Beaked Whale (Berardius bairdii) brain from Magnetic Resonance Imaging.

Brain, behavior and evolution·2026
Same journal

Immunohistochemical Staining of the Brain of the Tuatara Sphenodon punctatus.

Brain, behavior and evolution·2026
Same journal

Macroevolutionary patterns of endocast lateralization in catarrhines and fossil hominins.

Brain, behavior and evolution·2026
Same journal

Phylogenetic patterns and genomic correlates of pronounced neocortical reduction in New World monkeys.

Brain, behavior and evolution·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification
11:44

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification

Published on: March 24, 2023

5.0K

Comparative Primate Connectomics.

James K Rilling1,2,3,4,5, Martijn P van den Heuvel6,7,8

  • 1Department of Anthropology, Emory University, Atlanta, Georgia, USA.

Brain, Behavior and Evolution
|August 13, 2018
PubMed
Summary
This summary is machine-generated.

This study compares primate brain connectomes, revealing humans have unique neural connections for language and tool use. These findings highlight specialized brain wiring in primates, particularly humans.

Keywords:
ConnectivityDiffusion-weighted imagingFunctional MRITractography

More Related Videos

Author Spotlight: Streamlined Brain and Skull Modeling for Enhanced Neurosurgical Planning in NHP Research
06:33

Author Spotlight: Streamlined Brain and Skull Modeling for Enhanced Neurosurgical Planning in NHP Research

Published on: February 9, 2024

1.8K
A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.4K

Related Experiment Videos

Last Updated: Feb 6, 2026

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification
11:44

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification

Published on: March 24, 2023

5.0K
Author Spotlight: Streamlined Brain and Skull Modeling for Enhanced Neurosurgical Planning in NHP Research
06:33

Author Spotlight: Streamlined Brain and Skull Modeling for Enhanced Neurosurgical Planning in NHP Research

Published on: February 9, 2024

1.8K
A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.4K

Area of Science:

  • Neuroscience
  • Comparative Anatomy
  • Primate Biology

Background:

  • A connectome maps neural connections within a nervous system.
  • Comparing connectomes across species reveals evolutionary and functional insights.
  • Long-range brain connections are vital for efficiency but energetically costly.

Purpose of the Study:

  • To conduct a detailed comparison of connectomes specifically within the primate order.
  • To identify human-specific neural connections and compare them with nonhuman primates.
  • To explore the potential for comparative connectomics in understanding primate specializations.

Main Methods:

  • Utilizing diffusion-weighted imaging and tractography to analyze brain connectivity.
  • Comparing structural and functional connectivity in humans and nonhuman primates (e.g., macaques).
  • Examining white matter volume and histological data for connectivity metrics.

Main Results:

  • Larger primate brains tend to have fewer global white matter connections than smaller ones.
  • Humans exhibit more neural connections than expected, potentially concentrated in the prefrontal cortex.
  • Significant overlap exists between human and nonhuman primate structural and functional connectivity, with human-specific connections in language, imitation, and tool use areas.

Conclusions:

  • Comparative connectomics reveals specialized neural pathways in primates, especially humans, linked to complex cognitive functions.
  • Future research using diffusion tractography in diverse primate species can uncover adaptations to different ecological and social niches.
  • Establishing cortical homologies and refining tractography methods are crucial for future comparative studies and understanding the functional significance of connectivity variations.