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Published on: June 15, 2018
Branch-PCR constructed TP53 gene nanovector for potential cancer therapy
Longhuai Cheng1, Huiting Deng, Dejun Ma
1State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center (Tianjin), Collaborative Innovation Center of Chemical Science and Engineering, (Tianjin), College of Chemistry, Nankai University, Tianjin, 300071, China. zhenxi@nankai.edu.cn.
Abstract:
A novel and efficient branch PCR strategy has been used to construct a TP53 gene nanovector based on a pair of trimers as primers, which showed unique advantages compared to other existing systems for gene delivery and effective potential cancer therapy.
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