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Hemodialysis-related headache and how to prevent it

G Gozubatik-Celik1, D Uluduz2, B Goksan2

  • 1Department of Neurology, Bakirkoy Research and Training Hospital for Neurologic and Psychiatric Diseases, Istanbul, Turkey.

European Journal of Neurology
|August 14, 2018
PubMed

Insights

Hemodialysis-related headache (HRH) affects 35.4% of patients, often occurring post-dialysis. Managing high blood pressure and urea levels may help prevent HRH.

Area of Science:

  • Nephrology
  • Neurology

Background:

  • Hemodialysis (HD) can cause neurological side effects.
  • Headache is a common symptom in patients undergoing HD.

Purpose of the Study:

  • Determine the frequency, clinical characteristics, and triggers of HD-related headache (HRH).
  • Evaluate preventive strategies for reducing HRH.

Main Methods:

  • Included 494 patients, with comparative controls (CC) identified.
  • Correlated pre/post-dialysis blood pressure, blood urea nitrogen (BUN), and creatinine.
  • Determined urea reduction ratio during dialysis.

Main Results:

  • 175 patients (35.4%) were diagnosed with HRH, more common in males.
  • HRH onset averaged 2.9 hours post-HD, with bifrontal pain reported by 41.7%.
  • HRH patients showed higher pre-dialysis blood pressure and greater pre/post-dialysis blood pressure fluctuations.

Conclusions:

  • HRH is a significant issue in hemodialysis patients.
  • High BUN levels and pre-dialysis hypertension are associated with HRH.
  • Adjusting dialysis frequency and timing may aid HRH management.
Abstract

Keywords:
blood pressureblood urea nitrogendialysishemodialysis-related headache

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