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Updated: Feb 6, 2026

Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
Published on: August 31, 2022
Biomechanical study of optimum anchorage in dome-shaped high tibial osteotomy
Toshiaki Takahashi1,2, Manabu Takahashi3, Haruyasu Yamamoto2
11 Community Medical Support Center, Ehime University Hospital, Ehime, Japan.
Purpose:
There has been no report to date on any biomechanical study regarding the strength of fixation at the osteotomy site in dome-shaped high tibial osteotomy (HTO). In this study, we evaluated the biomechanical strength of a spacer that we improved and determined the medial site of HTO.
Methods:
HTO correction angles of 15° and 20° were used in all experiments, which were performed on lower leg specimens from pigs ( n = 12). The osteotomy site was fixed by a locking plate and screws with a spacer. Compression (600 N/min until 1100 N) and extended cyclic loading (200 cycles at 1000-2000 N) were performed to compare initial displacements in HTO specimens with and without spacers.
Results:
The reduction ratios of displacement with and without spacers at HTO correction angles of 15° and 20° were 37% and 27%, respectively. No effect of the spacer at the correction angle of 15° was observed in the cyclic loading; however, the maximum displacement and amplitude were reduced with the spacer at the correction angle of 20°.
Conclusions And Clinical Relevance:
When the HTO correction angle is small, the effect of the spacer is uncertain. However, the spacer is effective at an HTO correction angle of 20°.
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