Related Experiment Video
Updated: Feb 6, 2026
07:04
A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
8.9K
[Prurigo pigmentosa during pregnancy]
I Devred1, A Sfecci1, N Cardot-Leccia2
1Service de dermatologie, université Côte d'Azur, CHU, Nice, France.
Annales De Dermatologie Et De Venereologie
|August 15, 2018
Summary
Prurigo pigmentosa, a rare skin condition, can occur during pregnancy with severe vomiting. Managing ketonemia is key to controlling inflammatory flares and resolving this condition.
Area of Science:
- Dermatology
- Reproductive Medicine
Background:
- Prurigo pigmentosa is a rare inflammatory dermatosis presenting with pruritic, reticulate papules and subsequent hyperpigmentation.
- This condition is infrequently reported outside of Asian populations, and its pathophysiology remains largely unknown.
Observation:
- A case of prurigo pigmentosa is presented in a 21-year-old North-African woman during her first trimester of pregnancy.
- The patient experienced severe vomiting, leading to significant weight loss, ketonemia, and ketonuria, accompanied by a characteristic pruritic, reticular rash on her trunk.
Findings:
- The diagnosis of prurigo pigmentosa was confirmed through clinical presentation and histological examination.
- Disease progression showed fluctuations in inflammation and pruritus, linked to recurrent ketonemia, with resolution occurring in the second trimester as vomiting subsided.
Implications:
- This case highlights the importance of recognizing the clinical presentation of prurigo pigmentosa, even in non-Asian individuals.
- It underscores the necessity of screening for and managing ketonemia, particularly in pregnant patients with severe vomiting, to effectively control prurigo pigmentosa flares.
