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When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
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Contact-Lens Biosensors.

Ryan Chang Tseng1, Ching-Chuen Chen2, Sheng-Min Hsu3

  • 1Department of Biomedical Engineering, National Cheng Kung University, Tainan City 701, Taiwan. tsengryan@gmail.com.

Sensors (Basel, Switzerland)
|August 15, 2018
PubMed
Summary
This summary is machine-generated.

Wearable biosensors offer non-invasive health monitoring using tear fluid. This review explores tear fluid analysis for detecting diseases like diabetes and cancer, including advancements in contact lens biosensors.

Keywords:
biomarkerbiosensorcontact lenstearwearable device

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Area of Science:

  • Biomedical Engineering
  • Ophthalmology
  • Analytical Chemistry

Background:

  • Wearable devices are crucial for point-of-care diagnostics and personalized medicine.
  • Current wearables have limitations in monitoring physiological signals and biomechanics.
  • Emerging wearables utilize body fluids for continuous health monitoring.

Purpose of the Study:

  • To review tear fluid as a diagnostic medium for diseases.
  • To discuss the application of integrated contact lens biosensors.
  • To assess the practicality and progress of tear-based biosensing.

Main Methods:

  • Literature review of tear fluid analysis for disease detection.
  • Exploration of wearable biosensor technologies.
  • Analysis of contact lens biosensor development and applications.

Main Results:

  • Tear fluid is a promising medium for detecting ocular diseases, diabetes, and cancer due to its accessibility and minimal invasiveness.
  • Integrated contact lens biosensors represent a significant advancement in minimally invasive monitoring.
  • Tear-based biosensing offers potential for patient-oriented therapies and disease management.

Conclusions:

  • Tear fluid analysis via advanced biosensors holds significant potential for early disease detection and management.
  • Contact lens biosensors are advancing towards practical, real-time health monitoring.
  • This technology can reduce healthcare burdens and improve patient outcomes.