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Related Concept Videos

Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
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Anatomy of the Genitourinary System II: Bladder and Urethra01:19

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

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Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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What is Cancer?02:12

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Related Experiment Video

Updated: Feb 6, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
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Culture of Bladder Cancer Organoids as Precision Medicine Tools

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SnapShot: Bladder Cancer.

Carolyn Hurst1, Jonathan Rosenberg2, Margaret Knowles1

  • 1Leeds Institute of Cancer and Pathology, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.

Cancer Cell
|August 15, 2018
PubMed
Summary
This summary is machine-generated.

Bladder cancers, primarily urothelial carcinoma, present as muscle-invasive or non-muscle-invasive types. Recent genomic and transcriptomic data are improving tumor sub-classification and treatment strategies for these urinary tract cancers.

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Related Experiment Videos

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Area of Science:

  • Oncology
  • Urology

Background:

  • Bladder cancer, predominantly urothelial carcinoma, is the most frequent urinary tract malignancy.
  • It is classified into muscle-invasive and non-muscle-invasive types, each with unique molecular characteristics and clinical trajectories.

Purpose of the Study:

  • To summarize recent advancements in understanding bladder cancer subtypes.
  • To highlight the impact of genomic and transcriptomic data on prognostication and treatment.

Main Methods:

  • Review of recent genomic and transcriptomic studies in bladder cancer.
  • Analysis of data pertaining to tumor sub-classification and patient prognostication.

Main Results:

  • Genomic and transcriptomic data have enhanced the sub-classification of both muscle-invasive and non-muscle-invasive bladder cancers.
  • These molecular insights are crucial for improving prognostication and guiding treatment decisions, particularly for muscle-invasive disease.

Conclusions:

  • Recent molecular data are transforming the understanding and management of bladder cancer.
  • Improved sub-classification and prognostication are paving the way for more effective therapeutic approaches.