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Updated: Aug 18, 2026

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation
Published on: August 1, 2010
[Histogenesis of human embryonal cancer of the testis]
Abstract:
Complex morphological study of 45 germ cell tumors of the testis revealed two types of histological structure of embryonal carcinoma. Tumour histostructure was related to the ultrastructural features of cells (I-IV types) forming them. The data obtained indicate that the process of differentiation of these tumours resembles initial stages of embryogenesis (morula, blastula, egg cylinder). Embryonal carcinoma cells appeared to be tumor stem cells in the development of teratoma, chorionepithelioma, yolk sac tumour.
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