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Defining the Rhythmogenic Elements of Mammalian Breathing
Jan-Marino Ramirez1, Nathan Baertsch1
1Center for Integrative Brain Research, Seattle Children's Research Institute, University of Washington School of Medicine , Seattle, Washington.
Abstract:
Breathing's remarkable ability to adapt to changes in metabolic, environmental, and behavioral demands stems from a complex integration of its rhythm-generating network within the wider nervous system. Yet, this integration complicates identification of its specific rhythmogenic elements. Based on principles learned from smaller rhythmic networks of invertebrates, we define criteria that identify rhythmogenic elements of the mammalian breathing network and discuss how they interact to produce robust, dynamic breathing.
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