Early Variations in White Matter Microstructure and Depression Outcome in Adolescents With Subthreshold Depression

Hélène Vulser¹, Marie-Laure Paillère Martinot¹, Eric Artiges¹+38

• ¹From INSERM, Research Unit UMR 1000, Research Unit "Neuroimaging and Psychiatry," Paris; University Paris-Saclay, Gif-sur-Yvette, France; University Paris Descartes, Paris; Assistance Publique-Hôpitaux de Paris, Department of Psychiatry, Western Paris University Hospital group, Paris; Assistance Publique-Hôpitaux de Paris, Child and Adolescent Psychiatry Department, Pitié-Salpêtrière Hospital, Paris the Center for Neuroimaging Research, Brain and Spine Institute, Paris; the Department of Psychiatry, Orsay Hospital, Orsay, France; the Department of Social and Health Care, Psychosocial Services Adolescent Outpatient Clinic, Lahti, Finland; the Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; the Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy and the Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité-Universitätsmedizin Berlin; the Department of Child and Adolescent Psychiatry, the Centre for Neuroimaging Sciences, the Medical Research Council-Social, Genetic, and Developmental Psychiatry Centre, and the Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London; the University Medical Center Hamburg-Eppendorf, Hamburg; Neuroscience Paris Seine-IBPS (CNRS UMR8246/Inserm U1130/UMPC UMCR18); Centre National de la Recherche Scientifique, Research Unit UMR 8194, Paris; the Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neurosciences, Trinity College, Dublin; Physikalisch-Technische Bundesanstalt, Berlin; the Department of Psychiatry, University of Montreal, CHU Sainte-Justine Hospital, Montreal; Neurospin, Commissariat à l'Energie Atomique, CEA-Saclay Center, Paris; the Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg; the Departments of Psychiatry and Psychology, University of Vermont, Burlington; Sir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, U.K.; the Rotman Research Institute, University of Toronto, Toronto; the Department of Child and Adolescent Psychiatry and Psychotherapy, Medical University of Vienna, Austria; the Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany; the Department of Psychology, University College, Dublin.