Related Experiment Video
Updated: Feb 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Migraine and Non-Migraine Headaches Following Diagnostic Catheter-Based Cerebral Angiography
Adnan I Qureshi1,2, Nishath Naseem1,2, Muhammad A Saleem1,3
1Zeenat Qureshi Stroke Institute, St. Cloud, MN, USA.
Insights
Migraine headaches, an under-recognized adverse event, occurred in 3.1% of patients after cerebral angiography. This study quantifies the frequency and characteristics of these post-angiography headaches.
Area of Science:
- Neurology
- Radiology
- Clinical Medicine
Background:
- Headaches post-cerebral angiography are not well-documented.
- Catheter-based cerebral angiography is a common diagnostic procedure.
- Understanding adverse events is crucial for patient care.
Purpose of the Study:
- To determine the frequency of headaches after catheter-based cerebral angiography.
- To characterize the types and severity of these headaches.
- To identify potential risk factors for post-angiography headaches.
Main Methods:
- Observational cohort study design.
- Inclusion of consecutive patients undergoing transfemoral or radial cerebral angiography.
- Neurological assessment post-procedure, with detailed headache evaluation if reported.
- Classification of headaches using International Headache Society criteria.
- Assessment of headache severity and time to resolution.
Main Results:
- Migraine headaches occurred in 3.1% (95% CI 1.0-7.2%) of 158 patients.
- Median migraine severity was 10/10, with resolution in 120 minutes (range 60-360).
- Higher incidence in patients with pre-existing migraine history (18.1%).
Conclusions:
- Migraine headaches are an under-recognized adverse event following cerebral angiography.
- Provides crucial data on the occurrence rates of these headaches.
- Highlights the importance of recognizing and managing post-procedural headaches.
Background And Objective:
No reliable estimates of headaches following catheter-based cerebral angiography are available. We performed an observational cohort study to ascertain the frequency and type of headaches following catheter-based cerebral angiography.
Materials And Methods:
Consecutive patients who underwent cerebral angiography through the transfemoral (or infrequently radial) route were included. Each patient underwent a brief neurological assessment after the procedure and more detailed assessment was performed if any patient reported occurrence of a headache. The headaches were classified as migraine if the diagnostic criteria specified by International Headache Society were met. The headache severity was classified using a visual numeric rating scale and time to reach pain free status for 2 consecutive hours was ascertained.
Results:
Migraine headaches occurred in 5 (3.1%, 95% confidence interval [CI] 1.0-7.2%) of 158 patients who underwent cerebral angiography. The median severity of migraine headaches was 10/10 and time to resolution of headaches was 120 minutes (range 60-360 minutes). Migraine headaches occurred in 4 (18.1%, 95% CI 5.2-40.3%) of 22 patients with a history of migraine and 4 (23.5%, 95% CI 6.8-50%) of 17 patients with regular migraine headaches (≥1 episodes per month). Headaches occurred in 6 (3.8%, 95% CI 1.8-8.0%) patients who did not meet the criteria for migraine headaches.
Conclusions:
We provide occurrence rates of migraine headaches, an under-recognized adverse event, in patients undergoing catheter-based cerebral angiography.
Related Concept Videos
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Cerebral Hemispheres
Pericarditis II: Clinical Features and Diagnostic Tests
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

