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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Skin in Vitamin D Synthesis01:23

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Related Experiment Video

Updated: Feb 6, 2026

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels
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Published on: July 3, 2025

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Does vitamin C prevent the common cold?

Evelyn Gómez1, Sebastián Quidel1, Gonzalo Bravo-Soto2

  • 1Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, Chile.

Medwave
|August 17, 2018
PubMed
Summary

Vitamin C supplementation does not prevent the common cold. A comprehensive review of 45 studies, including 31 randomized trials, found no evidence that vitamin C prevents cold incidence.

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Area of Science:

  • Evidence-based medicine
  • Public health

Background:

  • The common cold is a prevalent illness with widespread public belief in vitamin C prevention.
  • The efficacy of vitamin C for preventing the common cold remains a subject of debate.

Purpose of the Study:

  • To critically evaluate the scientific evidence on vitamin C's effectiveness in preventing the common cold.
  • To synthesize findings from systematic reviews and primary studies.

Main Methods:

  • A systematic search was conducted using Epistemonikos, a large database of health-related systematic reviews.
  • Data from systematic reviews were extracted, primary study data reanalyzed, and a meta-analysis performed.
  • The GRADE approach was utilized to generate a summary of findings.

Main Results:

  • Eight systematic reviews were identified, encompassing 45 distinct studies.
  • A significant portion of the included studies (31) were randomized controlled trials.
  • The meta-analysis indicated no preventative effect of vitamin C on common cold incidence.

Conclusions:

  • The consumption of vitamin C does not prevent the occurrence of the common cold.
  • Current evidence does not support vitamin C supplementation for common cold prevention.
  • Further research may be warranted, but existing data suggest limited benefit.