Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of the Lymphatic System01:15

Development of the Lymphatic System

2.1K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.1K
Introduction to Lymphatic and Immune System01:22

Introduction to Lymphatic and Immune System

17.6K
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
17.6K
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

6.9K
The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
6.9K
Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

23.4K
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
23.4K
Reconstruction of Signal using Interpolation01:10

Reconstruction of Signal using Interpolation

735
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
735
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.9K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Social Media as a Platform for Cancer Care Decision-Making Among Women: Internet Survey-Based Study on Trust, Engagement, and Preferences.

JMIR cancer·2026
Same author

Surgeons, physiatrists and neurologists speaking "EDX and nerve surgery": A paradigm shift for nerve injured patients.

JPRAS open·2026
Same author

Discussion: Spinal Accessory Nerve Injury in Patients with Brachial Plexus Injury: Prevalence, Predisposing Factors, and Spontaneous Recovery.

Plastic and reconstructive surgery·2025
Same author

Epitrochlear and Humeral Lymph Nodes: A Biomarker for Deep Lymphatic Function and Implications for Breast Cancer-Related Lymphedema Risk.

Journal of surgical oncology·2025
Same author

Social Media as a Platform for Cancer Care Decision-Making Among Women: Internet Survey-Based Study on Trust, Engagement, and Preferences.

JMIR cancer·2025
Same author

Practicing Emotional Self-awareness to Build Surgeon Resilience.

Plastic and reconstructive surgery. Global open·2025
Same journal

Institutional Learning Curve in Esophagectomy: Technical Standardization of Gastric Conduit Formation and Conduit-Related Outcomes in 187 Consecutive Patients.

Journal of surgical oncology·2026
Same journal

Evaluating the Accuracy of ChatGPT-4o in Addressing Complex Clinical Questions Based on NCCN Guidelines for Rectal Adenocarcinoma.

Journal of surgical oncology·2026
Same journal

Racial Differences in Breast Cancer Treatment and Information Access.

Journal of surgical oncology·2026
Same journal

Comparative Analysis of CEM and Breast MRI: A Retrospective Study.

Journal of surgical oncology·2026
Same journal

The Treatment Efficacy for Patients Undergoing Combined Transanal-Transabdominal Endoscopic Resection of Rectal Anastomosis Stenosis.

Journal of surgical oncology·2026
Same journal

"It Depends on the Situation": Variability in How Surgical Oncologists Elicit and Integrate Patient Values.

Journal of surgical oncology·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

16.9K

Immediate lymphatic reconstruction.

Anna Rose Johnson1, Dhruv Singhal1

  • 1Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Journal of Surgical Oncology
|August 17, 2018
PubMed
Summary
This summary is machine-generated.

Chronic lymphedema lacks a cure, but immediate lymphatic reconstruction after lymphadenectomy offers a new preventive approach. This review explores the historical shift, evidence, and challenges of this microsurgical technique.

Keywords:
LYMPHAlymphatic reconstructionlymphedemamicrosurgery

More Related Videos

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics
08:08

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Published on: December 8, 2011

14.1K
Author Spotlight: Magnetic Bead-Based Isolation of Murine Dermal Lymphatic Endothelial Cells
05:52

Author Spotlight: Magnetic Bead-Based Isolation of Murine Dermal Lymphatic Endothelial Cells

Published on: July 21, 2023

2.7K

Related Experiment Videos

Last Updated: Feb 6, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

16.9K
Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics
08:08

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Published on: December 8, 2011

14.1K
Author Spotlight: Magnetic Bead-Based Isolation of Murine Dermal Lymphatic Endothelial Cells
05:52

Author Spotlight: Magnetic Bead-Based Isolation of Murine Dermal Lymphatic Endothelial Cells

Published on: July 21, 2023

2.7K

Area of Science:

  • Microsurgery
  • Lymphedema Management
  • Surgical Oncology

Background:

  • Chronic lymphedema remains incurable despite existing treatments.
  • Lymphadenectomy, often necessary for cancer treatment, can lead to lymphedema.
  • Microsurgical advances enable new preventive strategies.

Purpose of the Study:

  • To review the historical context and paradigm shift towards immediate lymphatic reconstruction.
  • To discuss the current evidence supporting this reconstructive approach.
  • To identify oncologic procedures suitable for simultaneous lymphatic reconstruction and outline challenges.

Main Methods:

  • Literature review of historical developments in lymphatic surgery.
  • Analysis of current evidence for immediate lymphatic reconstruction efficacy.
  • Identification of oncologic procedures and associated challenges.

Main Results:

  • A significant shift in surgical practice towards preventive lymphatic reconstruction.
  • Growing evidence supports the feasibility and potential benefits of immediate lymphatic reconstruction.
  • Specific oncologic surgeries identified as candidates for this approach.

Conclusions:

  • Immediate lymphatic reconstruction represents a paradigm shift in lymphedema prevention post-lymphadenectomy.
  • Further research and standardization are needed to address ongoing challenges and optimize outcomes.
  • This technique holds promise for improving quality of life in cancer survivors.