Related Experiment Video
Updated: Feb 6, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Skin Infections
Karl T Clebak1, Michael A Malone2
1Department of Family and Community Medicine, Penn State College of Medicine, 121 North Nyes Road, Harrisburg, PA 17112, USA.
Abstract:
The primary care provider will commonly see skin and soft tissue infections in the outpatient setting. Skin and soft tissue infections range from the uncomplicated impetigo to the potentially lethal necrotizing fasciitis. This article reviews these infections based on their underlying etiology: bacterial, fungal, and viral causes. This article discusses the etiology, presentation, evaluation, and management of impetigo, bullous impetigo, erysipelas, cellulitis, periorbital cellulitis, orbital cellulitis, folliculitis, furuncles, carbuncles, abscess, necrotizing fasciitis, sporotrichosis, tinea corporis, tinea pedis, tinea capitis, Herpes Simplex Virus, zoster, molluscum contagiosum, and warts.
Insights
This review covers common outpatient skin and soft tissue infections, detailing their bacterial, fungal, and viral causes. It guides primary care providers on diagnosing and managing conditions from impetigo to necrotizing fasciitis.
Area of Science:
- Dermatology
- Infectious Diseases
- Primary Care Medicine
Background:
- Skin and soft tissue infections (SSTIs) are frequently encountered in primary care.
- SSTIs present a spectrum of severity, from mild impetigo to life-threatening necrotizing fasciitis.
Purpose of the Study:
- To provide a comprehensive review of common SSTIs seen in outpatient settings.
- To categorize SSTIs by etiology: bacterial, fungal, and viral.
- To outline the etiology, presentation, evaluation, and management of various SSTIs.
Main Methods:
- Literature review of common SSTIs.
- Categorization of infections based on causative agents (bacterial, fungal, viral).
- Discussion of clinical presentation, diagnostic approaches, and treatment strategies.
Main Results:
- Detailed review of specific bacterial infections including impetigo, erysipelas, cellulitis, folliculitis, furuncles, carbuncles, abscesses, and necrotizing fasciitis.
- Overview of fungal infections such as sporotrichosis, tinea corporis, tinea pedis, and tinea capitis.
- Discussion of viral infections including Herpes Simplex Virus, zoster, molluscum contagiosum, and warts.
Conclusions:
- Primary care providers must be adept at recognizing and managing a wide array of SSTIs.
- Understanding the etiology is crucial for effective diagnosis and treatment of SSTIs.
- This review serves as a guide for the evaluation and management of common bacterial, fungal, and viral skin infections.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Accessory Structures of the Skin: Nails
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...

