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Updated: Feb 6, 2026

Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Emergence of Global Antibiotic Resistance
Martha Shawn Morehead1, Catherine Scarbrough2
1St. Vincent's East Family Medicine Residency, Christ Health Center, 2152 Old Springville Road, Birmingham, AL 35215, USA; Department of Family and Community Medicine, The University of Alabama at Birmingham School of Medicine, Community Health Services Building - 20th Street, 930 20th Street South, Suite 201, Birmingham, AL, 35294, USA; Department of Family Medicine, Alabama College of Osteopathic Medicine, 445 Health Sciences Boulevard, Dothan, AL 36303, USA.
Abstract:
Antibiotic resistance is a worldwide phenomenon and a global public health crisis. The inappropriate use of antibiotics in the human, animal, food, and agricultural arenas have contributed to the current dilemma. Both gram-positive and gram-negative resistant bacteria have been deemed serious and urgent threats by the Centers for Disease Control and Prevention. The World Health Organization has created a 5-objective global action plan to address antimicrobial resistance and to coordinate numerous international sectors. Antibiotic resistance affects both this generation and the next; thus, related ethical challenges, such as patient autonomy and justice have yet to be fully understood.
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