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Updated: Feb 6, 2026

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles
Published on: October 27, 2018
Synthesis of Complex Stereoheptads en Route to Daphnane Diterpene Orthoesters
Long V Nguyen1, Aaron B Beeler1
1Department of Chemistry , Boston University , 590 Commonwealth Avenue , Boston , Massachusetts 02215 , United States.
Abstract:
Tricyclic cores of the daphnane diterpene orthoesters (DDOs) are synthesized in 10 steps from readily available materials. Key to their assembly is the development of a stereocontrolled p-quinol functionalization sequence which enables rapid access to DDO C-ring stereopolyads from simple precursors. Problems encountered in stereo- and regioselectivity are highlighted and solved by exact changes in choreography, although it is shown that the undesired stereochemical outcomes also proceed with high selectivity.
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