Related Experiment Video

Updated: Feb 6, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
08:50

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

24.4K

Racial Disparities in Nephrology Consultation and Disease Progression among Veterans with CKD: An Observational

Jonathan Suarez1, Jordana B Cohen1,2, Vishnu Potluri1

  • 1Renal-Electrolyte and Hypertension Division, Department of Medicine, and.

Journal of the American Society of Nephrology : JASN
|August 19, 2018
PubMed

Insights

Racial disparities persist in chronic kidney disease (CKD) progression. Despite increased nephrology care access for Black and Hispanic veterans, they experience faster CKD progression, suggesting other factors influence outcomes.

Area of Science:

  • Nephrology
  • Health Disparities
  • Chronic Kidney Disease (CKD) Research

Background:

  • Incident rates of end-stage renal disease (ESRD) are disproportionately higher in Black and Hispanic populations compared to White patients.
  • Access to nephrology care before ESRD development is linked to improved clinical outcomes for patients with CKD.
  • It remains unclear if racial disparities in pre-ESRD nephrology consultation rates exist and if they contribute to worse outcomes among minority CKD patients.

Purpose of the Study:

  • To investigate racial disparities in nephrology consultation rates among veterans with chronic kidney disease (CKD).
  • To determine if these disparities contribute to differences in CKD progression and mortality.
  • To examine the association between nephrology care access and clinical outcomes in diverse CKD patient populations.

Main Methods:

  • A retrospective cohort study of Veterans Health Administration patients from 2003-2015.
  • Analysis focused on patients with incident CKD stage 4 and CKD stage 3.
  • Outcomes assessed included nephrology referral and visit rates, progression to CKD stage 5, and mortality.

Main Results:

  • Black and Hispanic veterans with CKD demonstrated higher rates of nephrology referral and visits compared to non-Hispanic white veterans.
  • Despite increased nephrology care, Black and Hispanic patients exhibited faster progression to CKD stage 5.
  • Mortality rates showed a slight decrease in Black patients with CKD stage 4 but a small increase in Black patients with CKD stage 3.

Conclusions:

  • Black and Hispanic veterans with CKD are more likely to receive nephrology care but still face more rapid disease progression.
  • Factors beyond nephrology consultation, potentially biologic and environmental, may drive racial disparities in CKD progression.
  • Further research is needed to understand and address the complex drivers of racial disparities in CKD outcomes.
Abstract

Keywords:
chronic kidney diseaseend stage kidney diseasehealth disparitiesnephrologyoutcomes

More Related Videos

A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS06:49

A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS

Published on: October 6, 2015

20.9K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.7K

Related Concept Videos

Observational Studies01:11

Observational Studies

Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.1K
Naturalistic Observations02:30

Naturalistic Observations

If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
17.4K
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.4K
Observational Learning01:12

Observational Learning

Albert Bandura's observational learning, also known as imitation or modeling, occurs when a person observes and imitates another's behavior. It is a quicker process than operant conditioning. A well-known example is the Bobo doll study, where children who saw an adult acting aggressively towards the doll were more likely to act aggressively when left alone, compared to those who observed a nonaggressive adult. Many psychologists view observational learning as a form of latent learning...
1000
Actor-Observer Effect01:23

Actor-Observer Effect

The actor-observer effect, a cognitive bias closely linked to the fundamental attribution error, refers to the tendency for individuals to attribute their behavior to external, situational factors while explaining others’ behavior in terms of internal, dispositional traits. This asymmetry in attribution significantly influences social perception and judgment.Cognitive Mechanisms Behind the EffectTwo primary psychological mechanisms contribute to the actor-observer effect: differences in...
401
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
4.8K