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Published on: February 14, 2022
[Easy screening of outpatients for atrial fibrillation by analyzing fingertip pulse wave variation]
Shinichi Okabe1, Akiyoshi Sato1, Hiromichi Kasuya1
1Seirei Memorial Hospital.
Insights
A novel pulse analysis method effectively screened for undiagnosed atrial fibrillation (AF) in over 16,000 outpatients, identifying 56 new cases. This approach shows promise for early detection and treatment of asymptomatic AF.
Area of Science:
- Cardiology
- Medical Diagnostics
- Public Health
Background:
- Atrial fibrillation (AF) is a common arrhythmia that significantly increases the risk of cardioembolic stroke.
- Undiagnosed or untreated AF in outpatient settings contributes to preventable strokes.
- Current diagnostic methods may miss asymptomatic AF cases in routine clinical practice.
Purpose of the Study:
- To evaluate the efficacy of a novel pulse analysis method for screening undiagnosed atrial fibrillation (AF) in hospital outpatients.
- To assess the benefits and accuracy of this pulse analysis technique in identifying asymptomatic AF.
- To determine the prevalence of newly detected AF in the screened outpatient population.
Main Methods:
- A pulse analysis software application was developed to analyze pulse interval variation.
- Screening was conducted on 16,356 hospital outpatients, primarily those over 65 years old.
- The accuracy and sensitivity of the pulse analysis method for AF detection were assessed.
Main Results:
- The pulse analysis method detected atrial fibrillation in 56 outpatients (1.1% of screened patients).
- The average age of patients diagnosed with AF was 76.9 years, with a high prevalence of risk factors (CHADS2 score >2, history of arrhythmia).
- The sensitivity of the screening device was 89.7%, indicating high accuracy in identifying AF.
Conclusions:
- The developed pulse analysis method is effective in detecting asymptomatic atrial fibrillation in an outpatient setting.
- This screening approach offers a valuable tool for identifying previously undiagnosed AF, enabling timely anticoagulation treatment.
- Implementing this pulse analysis screening can improve early detection rates of AF and potentially reduce stroke incidence.
Aim:
Atrial fibrillation (AF), which can lead to cardioembolic stroke, is often not properly diagnosed in hospital outpatient departments or medical clinics. We therefore used a pulse analysis to screen patients for AF, and examined the benefits of using this method in screening.
Methods:
We performed screening of the hospital's first-visit and ambulatory patients during the afternoon in 2014 (total number, 50,875; true number, 16,356), mainly targeting patients older than 65 years of age. Among the true number of outpatients, the device was used on 5,013 patients, 8,656 times. We independently developed a pulse analysis software application which analyzed the pulse interval variation. We assessed the accuracy of this analytical method in the detection of AF.
Results:
AF was detected in 56 patients, who were considered for or introduced to anticoagulation treatment. In their cases, the method was considered useful for detecting undiagnosed or untreated AF. This figure amounts to 0.34% of all outpatients and 1.1% of the patients who were screened in 2014. The average age was 76.9±7.7 years, 67.9% of the patients had a CHADS2 score of more than 2, half had a history of arrhythmia in the past, and 37.5% were first-visit patients. The sensitivity of the device used was 89.7%.
Conclusions:
Using the method described in this study, we detected asymptomatic AF in numerous patients, and demonstrated that this method is potentially useful in screening outpatients for asymptomatic AF.
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