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[Infectious endocarditis surgically treated during the acute phase. 26 cases].
Summary
Surgery for active infective endocarditis, especially on the aortic valve, can be life-saving. Echocardiographic vegetations and longer surgical times increase operative mortality risks.
Area of Science:
- Cardiology
- Infectious Diseases
- Cardiac Surgery
Context:
- Infective endocarditis (IE) poses significant risks, particularly in regions with limited diagnostic resources.
- Late diagnosis and active infection often necessitate surgical intervention during the acute phase.
Purpose:
- To evaluate the outcomes of surgical intervention for active infective endocarditis.
- To identify factors influencing operative mortality and long-term prognosis.
Summary:
- Twenty-six patients with active IE underwent surgery, with 24 native valve and 2 prosthetic valve cases.
- Overall mortality was 26%, primarily due to hemodynamic failure. Echocardiographic vegetations and operative times impacted mortality, while antibiotic duration and disease stage did not.
- Post-operative follow-up showed improved functional status and reduced cardiothoracic index.
Impact:
- Highlights the critical role of early surgical intervention in managing active IE, especially in resource-limited settings.
- Identifies key predictors of surgical outcomes, aiding in risk stratification and patient selection.
- Demonstrates the potential for improved long-term prognosis following successful surgical treatment of IE.