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Zika Virus Seropositivity in 1-4-Year-Old Children, Indonesia, 2014

R Tedjo Sasmono, Rama Dhenni, Benediktus Yohan

    Emerging Infectious Diseases
    |August 21, 2018
    PubMed

    Insights

    Zika virus seroprevalence was assessed in Indonesian children. Over 9% tested positive, indicating widespread Zika virus transmission and immunity in the population.

    Area of Science:

    • * Virology
    • * Epidemiology
    • * Public Health

    Background:

    • * Zika virus poses a significant global health threat.
    • * Understanding transmission dynamics is crucial for public health interventions.
    • * Data on Zika virus in Indonesia, particularly among children, is limited.

    Purpose of the Study:

    • * To determine the seroprevalence of Zika virus in healthy children aged 1-4 years in Indonesia.
    • * To assess the extent of recent Zika virus transmission and population immunity.

    Main Methods:

    • * Serum samples were collected from 662 healthy children aged 1-4 years.
    • * Samples were collected in 2014 from 30 urban sites across Indonesia.
    • * Zika virus serostatus was determined for each sample.

    Main Results:

    • * A total of 662 children's serum samples were analyzed.
    • * 9.1% of the children tested positive for Zika virus antibodies.
    • * This indicates a notable level of Zika virus exposure in the study population.

    Conclusions:

    • * The findings suggest widespread recent Zika virus transmission in Indonesia.
    • * A significant proportion of young children have developed immunity to Zika virus.
    • * Further research is recommended to ascertain the endemicity of Zika virus in Indonesia.

    Keywords:
    IndonesiaPRNTZika virusflavivirusplaque-reduction neutralizationprevalenceserologyseroprevalencevector-borne infectionsviruses

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