Related Experiment Video
Updated: Feb 6, 2026

Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
The Pharmacoeconomic Aspects of Antibiotic Stewardship Programs
1Antibiotic Stewardship Program, Division of Infectious Disease, Rhode Island Hospital, 593 Eddy Street, Physicians Office Building, Suite #328, Providence, RI 02903, USA.
Abstract:
Optimal antimicrobial therapy must take into account the key factors in antibiotic selection, that is, spectrum, tissue penetration, resistance potential, safety profile, and relative cost-effectiveness. The least expensive drug is usually accompanied by other concerns, such as high resistance potential, poor side effect profile, pharmacokinetic properties that limit penetration into target tissue (site of infection), and/or suboptimal activity against the presumed/known pathogen. It is false economy to preferentially select the least expensive antibiotics solely because of its acquisition cost. Therapeutic failure and hidden costs may make an apparently less expensive antibiotic most costly in the end.
Related Concept Videos
Antibiotic Selection
Quantitative Aspects of Drug-Receptor Interaction
Development of Antibiotic Resistance
Types of Genetic Transfer Between Organisms
The Roles of Bacteria and Fungi in Plant Nutrition
Self-Schemas

