Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functional Groups02:45

Functional Groups

89.0K
Functional groups are a group of atoms with characteristic properties, which when linked to the carbon skeleton of a molecule, alter the properties of that molecule. For example, the presence of certain functional groups on a molecule will make them hydrophilic, whereas others will make them hydrophobic. These functional groups are an indispensable part of organic chemistry and important components of biological molecules, such as carbohydrates, proteins, lipids, and nucleic acids. Each...
89.0K
Functional Groups02:45

Functional Groups

24.5K
24.5K
Functionalism01:11

Functionalism

2.6K
William James, John Dewey, and Charles Sanders Peirce were instrumental in founding functional psychology, which draws heavily from Darwin's theory of evolution by natural selection. This theory suggests that individual traits, including behaviors, are adapted to their environments through natural selection. At the heart of functionalism is the concept of adaptation, meaning that a trait enhances an individual's chances of survival and reproduction.
James envisioned psychology's...
2.6K
DC Generator01:19

DC Generator

2.1K
An alternator converts mechanical energy into electrical energy that varies sinusoidally, resulting in AC current. Meanwhile, a DC generator converts mechanical energy into electrical energy, which are DC pulses with the same polarity. The construction of a DC generator is similar to that of an alternator, except that the pair of slip rings is replaced by a single split ring, also called a commutator. The commutator functions like a periodic rotary switch; it changes the contacts with the...
2.1K
Mechanical Protein Functions01:58

Mechanical Protein Functions

5.6K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
5.6K
Structural Protein Function01:56

Structural Protein Function

30.0K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
30.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

To mesh or not mesh "apical prolapse," that is the question!

Neurourology and urodynamics·2024
Same author

Neuromodulation for Neurogenic Bladder.

Current bladder dysfunction reports·2019
Same author

Is the Diabetic Bladder a Neurogenic Bladder? Evidence from the Literature.

Current bladder dysfunction reports·2019
Same author

Commentary on "Prognostic effect of carcinoma in situ in muscle-invasive urothelial carcinoma patients receiving neoadjuvant chemotherapy."

Urologic oncology·2018
Same author

Conditional Electrical Stimulation in Animal and Human Models for Neurogenic Bladder: Working Toward a Neuroprosthesis.

Current bladder dysfunction reports·2016
Same author

A GENERIC PACKAGING TECHNIQUE USING FLUIDIC ISOLATION FOR LOW-DRIFT IMPLANTABLE PRESSURE SENSORS.

International Solid-State Sensors, Actuators and Microsystems Conference : [proceedings]. International Conference on Solid-State Sensors, Actuators, and Microsystems·2016
Same journal

Effective Mentorship in Urology Fellowship Training: Qualities, Models, and Equity.

Current urology reports·2026
Same journal

Management of Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis.

Current urology reports·2026
Same journal

Lower Urinary Tract Symptoms as an Indicator of Occult Neurologic Disease: A System-first Framework for Urologic Practice.

Current urology reports·2026
Same journal

Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.

Current urology reports·2026
Same journal

Is Open Partial Nephrectomy Still an Option in the Robotic Era?

Current urology reports·2026
Same journal

Artificial Intelligence in Urologic Documentation: A Review of Emerging Capabilities and the Ongoing Need for Human Oversight.

Current urology reports·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice
03:26

Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice

Published on: August 1, 2025

770

Troubleshooting Interstim Sacral Neuromodulation Generators to Recover Function.

C R Powell1

  • 1Department of Urology, Indiana University School of Medicine, 535 Barnhill Dr., Suite 420, Indianapolis, IN, 46202, USA. crpowell@iupui.edu.

Current Urology Reports
|August 22, 2018
PubMed
Summary
This summary is machine-generated.

Sacral neuromodulation (SNM) reprogramming can salvage devices and improve patient outcomes. This systematic strategy helps troubleshoot SNM generators, potentially avoiding revision surgery and ensuring sustained symptom control.

Keywords:
BladderElectric stimulationEquipment safetyNeuromodulationProsthesis and implantsUrinary frequencyUrinary incontinenceUrinary urgency

More Related Videos

Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies
09:00

Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies

Published on: May 22, 2012

410.4K
Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays
04:00

Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays

Published on: May 3, 2024

1.9K

Related Experiment Videos

Last Updated: Feb 6, 2026

Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice
03:26

Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice

Published on: August 1, 2025

770
Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies
09:00

Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies

Published on: May 22, 2012

410.4K
Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays
04:00

Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays

Published on: May 3, 2024

1.9K

Area of Science:

  • Urology
  • Neuromodulation
  • Medical Devices

Background:

  • Sacral neuromodulation (SNM) is increasingly used for lower urinary tract symptoms (LUTS).
  • Implanted SNM generators are common, requiring management strategies for complications.
  • Pain at the implant site (up to 53%) and loss of effective stimulation (3-38%) are known SNM complications.

Purpose of the Study:

  • To present a systematic strategy for reprogramming and troubleshooting SNM generators.
  • To provide clinicians with a methodology to salvage SNM devices.
  • To reduce the need for surgical revision or additional therapies for SNM patients.

Main Methods:

  • Development of standardized algorithms for SNM generator reprogramming.
  • Systematic troubleshooting approach for common SNM-related issues.
  • Review of literature regarding SNM device management and failure rates.

Main Results:

  • Reprogramming can salvage many SNM generators, avoiding revision surgery.
  • A systematic approach may increase the number of patients with persistent SNM benefit.
  • Lack of standardized troubleshooting protocols in current literature.

Conclusions:

  • A systematic strategy for SNM reprogramming can effectively troubleshoot devices.
  • This approach can salvage SNM generators, improving patient outcomes.
  • Standardized algorithms are crucial for managing SNM complications and ensuring long-term efficacy.