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Visible-Light-Promoted C(sp3)-C(sp2) Cross-Dehydrogenative Coupling of Tertiary Amine with Imidazopyridine
Golam Kibriya1, Avik Kumar Bagdi2, Alakananda Hajra1
1Department of Chemistry , Visva-Bharati (A Central University) , Santiniketan 731235 , India.
Abstract:
A metal-free visible-light-promoted C(sp3)-C(sp2) cross-dehydrogenative coupling between tetrahydroisoquinoline and imidazo[1,2- a]pyridine has been developed to afford 3-substituted imidazopyridines using a catalytic amount of rose bengal as photosensitizer under aerobic conditions. The present methodology is also applicable to imidazo[1,2- a]pyrimidine, indolizine, indole, and pyrrole as well as N, N-dimethyl aniline. Wide substrates scope, use of organo photocatalyst, metal-free, and mild reaction conditions are the attractive features of this methodology.
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