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Cyclodialysis cleft repair: A multi-centred, retrospective case series

Marko Popovic1, Shakeel Shareef2, Juan J Mura3

  • 1Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Clinical & Experimental Ophthalmology
|August 24, 2018
PubMed

Insights

Treatment for cyclodialysis clefts, a rare condition, shows high success rates. Most patients achieved significant visual acuity improvement and cleft closure, often requiring surgery, with better outcomes linked to initial visual acuity and intraocular pressure.

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Retinal Diseases

Background:

  • Cyclodialysis clefts are rare and evidence on their treatment is limited.
  • This study investigates outcomes of treating cyclodialysis clefts across six international centers.

Observation:

  • A retrospective case series included 36 patients diagnosed with cyclodialysis clefts between 2003 and 2017.
  • Treatments comprised cycloplegic agents, laser therapy, and/or surgical interventions.
  • Key outcome measures included postoperative best-recorded visual acuity (BRVA), intraocular pressure (IOP), and cleft closure rates.

Findings:

  • High closure rates (93.8%) were achieved, with most eyes eventually requiring surgery.
  • Significant improvements in BRVA (over two lines) were observed in over 80% of eyes.
  • Postoperative stabilized IOP (≥12 mmHg) was achieved in 80.6% of eyes, with only two eyes requiring IOP-lowering medication at follow-up.

Implications:

  • Improved postoperative BRVA was significantly correlated with better preoperative BRVA and higher preoperative IOP.
  • The findings suggest that surgical intervention is often necessary for successful cyclodialysis cleft closure and visual acuity improvement.
  • Effective management strategies can lead to favorable visual and IOP outcomes in patients with cyclodialysis clefts.
Abstract

Keywords:
ciliary body injuriescyclodialysis cleftgonioscopyintraocular pressurenonpenetrating trauma

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