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A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
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Ter-cell, A New Target for Hepatocellular Carcinoma Therapy
1Guangdong Provincial Key Laboratory of New Drug Screening and, Guangzhou Key Laboratory of Drug Research for, Emerging Virus Prevention and Treatment, School of, Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Abstract:
Hepatocellular carcinoma (HCC), a malignancy of the liver, has become the second most lethal cause of cancer death globally. Recently, scientists discovered that a splenic erythroblast-like cell induced by the primary tumor, termed Ter-cell, promoted HCC progression and metastasis. These findings shed light on the inhibition of Ter-cell or artemin that can serve as a new therapeutic target for HCC.
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