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Headache Characteristics in Children With Pseudotumor Cerebri Syndrome, Elevated Opening Pressure Without

Ali G Hamedani1, Kailyn F R Witonsky2, Mahgenn Cosico2

  • 1Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Headache
|August 24, 2018
PubMed

Insights

Headache in pediatric pseudotumor cerebri syndrome (PTCS) often involves the head, neck, and shoulders, and can be episodic or constant. Some children with PTCS experience no headache.

Area of Science:

  • Pediatric Neurology
  • Ophthalmology
  • Neuroscience

Background:

  • Headache is a common symptom attributed to increased intracranial pressure.
  • Systematic studies on headache characteristics in pediatric pseudotumor cerebri syndrome (PTCS) are limited, especially with revised diagnostic criteria.
  • Understanding these characteristics is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To systematically investigate headache characteristics in children diagnosed with or suspected of having PTCS.
  • To compare headache patterns and locations between children with definite/probable PTCS and those with elevated or normal intracranial pressure without papilledema.

Main Methods:

  • Retrospective cohort study of 127 pediatric patients treated for suspected or confirmed PTCS.
  • Chart review to assess PTCS diagnostic criteria, headache characteristics, and associated symptoms.
  • Chi-squared or Fisher's exact tests to compare headache frequencies between groups.

Main Results:

  • Headache involving the head, neck, or shoulders was more frequent in definite PTCS patients compared to controls (OR=7.2 and 4.5, respectively).
  • Headache patterns varied, with episodic headaches in 49% of definite PTCS cases.
  • Eleven children (8.7%) reported no headache, including some with definite or probable PTCS.

Conclusions:

  • Headache in pediatric PTCS frequently involves the head, neck, and shoulders.
  • Headache presentation in PTCS can be episodic or constant, and is occasionally absent.
  • Further research with larger cohorts is needed to confirm these findings.
Abstract

Keywords:
childrenheadacheidiopathic intracranial hypertensionmigraineopening pressurepseudotumor cerebri

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