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Oxygen Reserve Index: Validation of a New Variable.
Jaap Jan Vos1, Cornelis H Willems1, Kai van Amsterdam1
1From the Department of Anesthesiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Anesthesia and Analgesia
|August 24, 2018
Summary
The new Oxygen Reserve Index (ORi) shows a strong correlation with partial pressure of oxygen (PaO2), offering a promising noninvasive method for monitoring oxygenation status in patients receiving supplemental oxygen.
Area of Science:
- Medical Devices
- Physiology
- Respiratory Monitoring
Background:
- Standard pulse oximetry is limited in hyperoxia and normoxia.
- Oxygen Reserve Index (ORi) is a novel indicator for monitoring partial pressure of oxygen (PaO2).
Purpose of the Study:
- To validate the noninvasive Oxygen Reserve Index (ORi) against measured partial pressure of oxygen (PaO2).
- To assess ORi's ability to trend oxygenation status and predict hypoxia.
Main Methods:
- Prospective validation study with 20 healthy volunteers.
- Breathing standardized oxygen from hypoxia to hyperoxia.
- Noninvasive ORi measurement using multiwavelength pulse co-oximetry.
- Comparison of ORi values with invasive PaO2 measurements.
Main Results:
- Strong positive correlation between ORi and PaO2 (R = 0.78-0.83, P < .0001).
- Good trending ability of ORi for PaO2 (94% concordance rate).
- Effective prediction of hypoxia (PaO2 <100 mm Hg) with AUC of 0.91.
Conclusions:
- ORi demonstrates a strong correlation and good trending ability with PaO2.
- ORi shows potential as a continuous, noninvasive tool for oxygenation monitoring.
- Further use of ORi in patients receiving supplemental oxygen may be supported.
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