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Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report

Kana Fukumoto1, Yasuhiro Manabe1, Shunya Fujiwara1

  • 1Department of Neurology, National Hospital Organization Okayama Medical Center, Okayama, Japan.

Case Reports in Neurology
|August 25, 2018
PubMed

Insights

This case report details rare meningitis caused by Streptococcus mitis and Neisseria subflava in an elderly patient with diabetes and rheumatoid arthritis. Prompt antibiotic treatment led to a full recovery.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Microbiology

Background:

  • An 80-year-old female with a history of type II diabetes mellitus and rheumatoid arthritis, treated with immunosuppressants, presented with neurological symptoms.
  • The patient had recently undergone dental implant removal, a potential trigger for infection.

Observation:

  • The patient exhibited altered consciousness and convulsions, indicative of central nervous system involvement.
  • Cerebrospinal fluid analysis revealed a rare co-infection with Streptococcus mitis and Neisseria subflava.

Findings:

  • Both Streptococcus mitis and Neisseria subflava, typically commensal bacteria, were identified as causative agents of meningitis.
  • The patient received 14 days of ceftriaxone, resulting in significant clinical improvement.

Implications:

  • This case highlights the potential pathogenicity of ordinarily benign bacteria in immunocompromised individuals.
  • Risk factors for such infections include advanced age, immunosuppression, diabetes mellitus, and recent dental procedures.
Keywords:
Bacterial meningitisCompromised hostNeisseria subflavaStreptococcus mitis

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