Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is an Electrochemical Gradient?01:26

What is an Electrochemical Gradient?

128.1K
Adenosine triphosphate, or ATP, is considered the primary energy source in cells. However, energy can also be stored in the electrochemical gradient of an ion across the plasma membrane, which is determined by two factors: its chemical and electrical gradients.
The chemical gradient relies on differences in the abundance of a substance on the outside versus the inside of a cell and flows from areas of high to low ion concentration. In contrast, the electrical gradient revolves around an...
128.1K
Energy Line and Hydraulic Gradient Line01:27

Energy Line and Hydraulic Gradient Line

2.3K
Based on Bernoulli's equation, the energy line (EL) and hydraulic grade line (HGL) provide graphical representations of energy distribution in a fluid flow system. For steady, incompressible, inviscid flows, Bernoulli's equation is expressed as:
2.3K
Gradient and Del Operator01:14

Gradient and Del Operator

4.5K
In mathematics and physics, the gradient and del operator are fundamental concepts used to describe the behavior of functions and fields in space. The gradient is a mathematical operator that gives both the magnitude and direction of the maximum spatial rate of change. Consider a person standing on a mountain. The slope of the mountain at any given point is not defined unless it is quantified in a particular direction. For this reason, a "directional derivative" is defined, which is a vector...
4.5K
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis00:59

Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis

335
Noncompartmental analyses offer an alternative method for describing drug pharmacokinetics without relying on a specific compartmental model. In this approach, the drug's pharmacokinetics are assumed to be linear, with the terminal phase log-linear. This assumption allows for simplified analysis and interpretation of the drug's behavior in the body.
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
335
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

901
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
901
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches01:14

Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches

541
Drug disposition in the body is a complex process and can be studied using two major approaches: the model and the model-independent approaches.
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
541

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mycobacterium abscesses infection after TMJ arthroscopy.

International journal of oral and maxillofacial surgery·2026
Same author

Breaking barriers in extensively drug-resistant TB: pretomanid-centred long regimen achieves cure in a bedaquiline-resistant strain.

IJTLD open·2026
Same author

Explainable AI-Based Hyperspectral Classification Reveals Differences in Spectral Response over Phenological Stages.

Biology·2026
Same author

Lipegfilgrastim for primary prophylaxis of febrile neutropenia in patients treated for advanced-stage classical hodgkin lymphoma: successful outcomes from a multicenter cohort study.

Annals of hematology·2026
Same author

Protocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009).

Trials·2026
Same author

Search for Postinflationary QCD Axions with a Quantum-Limited Tunable Microwave Receiver.

Physical review letters·2025
Same journal

Evaluating a Novel Cell-Free Preservation Solution for Human Cardiomyocyte Protection: A Proof-of-Concept Study.

BioMed research international·2026
Same journal

Clinical Efficacy of Chinese Medicine in Treating Adult Henoch-Schönlein Purpura: A Meta-Analysis.

BioMed research international·2026
Same journal

RETRACTION: Rehabilitation Training and Resveratrol Improve the Recovery of Neurological and Motor Function in Rats after Cerebral Ischemic Injury through the Sirt1 Signaling Pathway.

BioMed research international·2026
Same journal

The Oncogenic and Tumor-Suppressive Roles of SNHG18: A Double-Edged Long Noncoding RNA in Cancer.

BioMed research international·2026
Same journal

Evaluation of LncRNA NEAT1 and MEG3 Expression Levels in Hospitalized COVID-19 Patients.

BioMed research international·2026
Same journal

Perceived Self-Efficacy and Its Determinants for Noncommunicable Disease Prevention Among Adults in Southern Ethiopia: A Community-Based Cross-Sectional Study.

BioMed research international·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.3K

A Gradient-Based Approach for Breast DCE-MRI Analysis.

L Losurdo1, T M A Basile2,3, A Fanizzi1

  • 1I.R.C.C.S. "Giovanni Paolo II" National Cancer Centre, Bari, Italy.

Biomed Research International
|August 25, 2018
PubMed
Summary
This summary is machine-generated.

This study introduces a new method using statistical measurements to analyze breast Magnetic Resonance Imaging (MRI) enhancement patterns. This aims to improve early breast cancer detection by aiding radiologists in identifying lesions, even with variable background parenchymal enhancement.

More Related Videos

Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI
08:36

Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI

Published on: March 6, 2014

19.7K
A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.4K

Related Experiment Videos

Last Updated: Feb 6, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.3K
Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI
08:36

Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI

Published on: March 6, 2014

19.7K
A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.4K

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Breast cancer is a leading cause of female mortality globally.
  • Early detection via imaging is crucial for reducing breast cancer mortality, especially in high-risk women.
  • Breast Magnetic Resonance Imaging (MRI) is vital for breast disease management, but background parenchymal enhancement can complicate lesion detection.

Purpose of the Study:

  • To develop an automated method for characterizing breast tissue enhancement trends in MRI.
  • To provide a diagnostic support tool for radiologists to overcome challenges posed by background parenchymal enhancement.
  • To independently analyze normal and abnormal tissue enhancement patterns for improved breast cancer diagnosis.

Main Methods:

  • Exploitation of statistical measurements to characterize enhancement trends.
  • Independent analysis of normal and abnormal breast tissue enhancement.
  • Development of an automated approach for MRI analysis.

Main Results:

  • The study investigates statistical measurements for characterizing enhancement trends.
  • The proposed method aims to differentiate enhancement patterns in normal versus abnormal tissues.
  • The approach is designed to be independent of background parenchymal enhancement variations.

Conclusions:

  • Statistical measurements can potentially characterize breast MRI enhancement trends.
  • This automated approach may assist radiologists in detecting and classifying breast lesions.
  • The method offers a novel way to support diagnostic accuracy in breast MRI analysis.